Tyrosine-Protein Kinase FRK

Preferred Label : Tyrosine-Protein Kinase FRK;

NCIt synonyms : GTK; GTK Homolog; RAK; Nuclear Tyrosine Protein Kinase RAK; FYN-Related Kinase; EC 2.7.10.2; Protein-Tyrosine Kinase 5;

NCIt definition : Tyrosine-protein kinase FRK (505 aa, 58 kDa) is encoded by the human FRK gene. This protein plays a role in tyrosine phosphorylation and the negative regulation of cell proliferation.;

Details

Origin ID

C29586;

UMLS CUI

C1384553;

OMIM relation
- Fyn-related src family tyrosine kinase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- FRK protein, human [MeSH Supplementary Concept]
- FRK protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- FRK Gene [NCIt concept]
- Kinase Family Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- SRC Family Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- SH2 Domain [NCIt concept]
- SH3 Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
- Tyrosine Kinase Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Differentiation Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Proliferation [NCIt concept]
- Inhibition of Cell Proliferation [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Signal Transduction [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]

Keyword's position in hierarchy(ies) :

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