" /> src homology domains - CISMeF





Preferred Label : src homology domains;

MeSH definition : Regions of AMINO ACID SEQUENCE similarity in the SRC-FAMILY TYROSINE KINASES that fold into specific functional tertiary structures. The SH1 domain is a CATALYTIC DOMAIN. SH2 and SH3 domains are protein interaction domains. SH2 usually binds PHOSPHOTYROSINE-containing proteins and SH3 interacts with CYTOSKELETAL PROTEINS.;

MeSH synonym : sh domain; homology domain, src; homology domains, src; sh domains; src homology domain;

MeSH hyponym : SH2 domain; SH1 domain; SH3 domain; SH2 Domains; src Homology Region 2 Domain; SH3 Domains; SH1 Domains;

Détails


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Regions of AMINO ACID SEQUENCE similarity in the SRC-FAMILY TYROSINE KINASES that fold into specific functional tertiary structures. The SH1 domain is a CATALYTIC DOMAIN. SH2 and SH3 domains are protein interaction domains. SH2 usually binds PHOSPHOTYROSINE-containing proteins and SH3 interacts with CYTOSKELETAL PROTEINS.

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27/07/2025


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