src homology domains

Preferred Label : src homology domains;

MeSH definition : Regions of AMINO ACID SEQUENCE similarity in the SRC-FAMILY TYROSINE KINASES that fold into specific functional tertiary structures. The SH1 domain is a CATALYTIC DOMAIN. SH2 and SH3 domains are protein interaction domains. SH2 usually binds PHOSPHOTYROSINE-containing proteins and SH3 interacts with CYTOSKELETAL PROTEINS.;

MeSH synonym : sh domain; homology domain, src; homology domains, src; sh domains; src homology domain;

MeSH hyponym : SH2 domain; SH1 domain; SH3 domain; SH2 Domains; src Homology Region 2 Domain; SH3 Domains; SH1 Domains;

Details

Origin ID

D018909;

UMLS CUI

C0282536;

Allowable qualifiers
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- immunology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- SH2 Domain [NCIt concept]
- SH3 Domain [NCIt concept]
Indexing information
- ASAP1 protein, human [MeSH Supplementary Concept]
- BAIAP2 protein, human [MeSH Supplementary Concept]
- BCAR3 protein, human [MeSH Supplementary Concept]
- BEM1 protein, candida albicans [MeSH Supplementary Concept]
- Bin1 protein, mouse [MeSH Supplementary Concept]
- CASS4 protein, Xenopus [MeSH Supplementary Concept]
- CD2-associated protein [MeSH Supplementary Concept]
- CRKL protein [MeSH Supplementary Concept]
- DAPP1 protein, human [MeSH Supplementary Concept]
- Dapp1 protein, mouse [MeSH Supplementary Concept]
- EAST protein, drosophila [MeSH Supplementary Concept]
- EAST protein, human [MeSH Supplementary Concept]
- Eat2a protein, mouse [MeSH Supplementary Concept]
- Eat2b protein, mouse [MeSH Supplementary Concept]
- FCHSD1 protein, human [MeSH Supplementary Concept]
- FCHSD2 protein, human [MeSH Supplementary Concept]
- GRAP2 protein, human [MeSH Supplementary Concept]
- HSH2 protein, mouse [MeSH Supplementary Concept]
- HSH2D protein, human [MeSH Supplementary Concept]
- IMP2 protein, S pombe [MeSH Supplementary Concept]
- INPPL1 protein, human [MeSH Supplementary Concept]
- Lsb3 protein, S cerevisiae [MeSH Supplementary Concept]
- MOB2 protein, human [MeSH Supplementary Concept]
- NCKIPSD protein, human [MeSH Supplementary Concept]
- NPHP1 protein, human [MeSH Supplementary Concept]
- NPHP4 protein, human [MeSH Supplementary Concept]
- Nphp1 protein, mouse [MeSH Supplementary Concept]
- PEX13 protein, human [MeSH Supplementary Concept]
- Pex13 protein, mouse [MeSH Supplementary Concept]
- Ptpns1 protein, mouse [MeSH Supplementary Concept]
- SH2B1 protein, rat [MeSH Supplementary Concept]
- SH2B2 protein, human [MeSH Supplementary Concept]
- SH2B3 protein, human [MeSH Supplementary Concept]
- SH2D1A protein, human [MeSH Supplementary Concept]
- SH2D1B protein, human [MeSH Supplementary Concept]
- SH2D3A protein, human [MeSH Supplementary Concept]
- SH2D3C protein, human [MeSH Supplementary Concept]
- SH3BGRL protein, human [MeSH Supplementary Concept]
- SH3BP2 protein, human [MeSH Supplementary Concept]
- SH3D19 protein, human [MeSH Supplementary Concept]
- SH3GL1 protein, human [MeSH Supplementary Concept]
- SH3GL2 protein, human [MeSH Supplementary Concept]
- SH3GL3 protein, human [MeSH Supplementary Concept]
- SH3GLB1 protein, human [MeSH Supplementary Concept]
- SH3PXD2A protein, human [MeSH Supplementary Concept]
- SH3TC2 protein, human [MeSH Supplementary Concept]
- SHC3 protein, human [MeSH Supplementary Concept]
- SHD protein, human [MeSH Supplementary Concept]
- SLA protein, human [MeSH Supplementary Concept]
- SLA2 protein, human [MeSH Supplementary Concept]
- SNX9 protein, human [MeSH Supplementary Concept]
- SOCS7 protein, human [MeSH Supplementary Concept]
- SORBS3 protein, human [MeSH Supplementary Concept]
- STAM protein, human [MeSH Supplementary Concept]
- STAMBP protein, human [MeSH Supplementary Concept]
- Sh2b2 protein, mouse [MeSH Supplementary Concept]
- Sh2b3 protein, rat [MeSH Supplementary Concept]
- Sh2bpsm1 protein, mouse [MeSH Supplementary Concept]
- Sh2d1a protein, mouse [MeSH Supplementary Concept]
- Sh2d1b1 protein, mouse [MeSH Supplementary Concept]
- Sh2d3c protein, mouse [MeSH Supplementary Concept]
- Sh3bp2 protein, mouse [MeSH Supplementary Concept]
- Sh3d19 protein, mouse [MeSH Supplementary Concept]
- Sh3gl2 protein, mouse [MeSH Supplementary Concept]
- Sh3kbp1 protein, mouse [MeSH Supplementary Concept]
- Sh3kbp1 protein, rat [MeSH Supplementary Concept]
- Sh3md2 protein, mouse [MeSH Supplementary Concept]
- Sh3rf3 protein, mouse [MeSH Supplementary Concept]
- Shc3 protein, mouse [MeSH Supplementary Concept]
- Shc3 protein, rat [MeSH Supplementary Concept]
- Sla2 protein, mouse [MeSH Supplementary Concept]
- Sorbs3 protein, mouse [MeSH Supplementary Concept]
- Sorbs3 protein, rat [MeSH Supplementary Concept]
- Stam2 protein, mouse [MeSH Supplementary Concept]
- TARSH protein, mouse [MeSH Supplementary Concept]
- Tns3 protein, mouse [MeSH Supplementary Concept]
- capt protein, drosophila [MeSH Supplementary Concept]
- cytokine inducible SH2-containing protein [MeSH Supplementary Concept]
- endophilin 3, rat [MeSH Supplementary Concept]
- endophilin A, drosophila [MeSH Supplementary Concept]
- endophilin A1 protein, mouse [MeSH Supplementary Concept]
- fish protein, mouse [MeSH Supplementary Concept]
- focal adhesion protein, 52-kDa [MeSH Supplementary Concept]
- intersectin 1 [MeSH Supplementary Concept]
- lnk protein, mouse [MeSH Supplementary Concept]
- melanoma inhibitory activity protein 2, mouse [MeSH Supplementary Concept]
- mona protein, mouse [MeSH Supplementary Concept]
- osteoclast stimulating factor [MeSH Supplementary Concept]
- p70 Jak2-interacting protein, mouse [MeSH Supplementary Concept]
- phocein [MeSH Supplementary Concept]
- sh3gl3b protein, zebrafish [MeSH Supplementary Concept]
- shd protein, mouse [MeSH Supplementary Concept]
- she protein, mouse [MeSH Supplementary Concept]
- sla protein, mouse [MeSH Supplementary Concept]
- sla protein, rat [MeSH Supplementary Concept]
- spri protein, drosophila [MeSH Supplementary Concept]
- stam protein, mouse [MeSH Supplementary Concept]
- stambp protein, mouse [MeSH Supplementary Concept]
Record concept(s)
- SH1 domain [MeSH concept]
- SH2 domain [MeSH concept]
- SH3 domain [MeSH concept]
- src homology domains [MeSH concept]
Related MeSH Supplementary Concept(s)
- DBNL protein, human [MeSH Supplementary Concept]
- dbnl protein, mouse [MeSH Supplementary Concept]
- dbnl protein, rat [MeSH Supplementary Concept]
See also
- SH2 Domain-Containing protein tyrosine phosphatases [MeSH Descriptor]
- Syk Kinase [MeSH Descriptor]
- TYK2 kinase [MeSH Descriptor]
- ZAP-70 protein-tyrosine kinase [MeSH Descriptor]
- genes, src [MeSH Descriptor]
- janus kinase 1 [MeSH Descriptor]
- janus kinase 2 [MeSH Descriptor]
- janus kinase 3 [MeSH Descriptor]
- janus kinases [MeSH Descriptor]
- protein tyrosine phosphatase, Non-Receptor type 6 [MeSH Descriptor]
- protein-tyrosine kinases [MeSH Descriptor]
- proto-oncogene proteins c-vav [MeSH Descriptor]
- src-Family kinases [MeSH Descriptor]
- stat1 transcription factor [MeSH Descriptor]
- stat3 transcription factor [MeSH Descriptor]
Semantic type(s)
- Amino Acid Sequence [UMLS semantic type]

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