MeSH definition : A signal transducer and activator of transcription that mediates cellular responses
to INTERLEUKIN-6 family members. STAT3 is constitutively activated in a variety of
TUMORS and is a major downstream transducer for the CYTOKINE RECEPTOR GP130.;
A signal transducer and activator of transcription that mediates cellular responses
to INTERLEUKIN-6 family members. STAT3 is constitutively activated in a variety of
TUMORS and is a major downstream transducer for the CYTOKINE RECEPTOR GP130.