janus kinase 3

Preferred Label : janus kinase 3;

MeSH definition : A Janus kinase subtype that is predominantly expressed in hematopoietic cell. It is involved in signaling from a broad variety of CYTOKINE RECEPTORS including ones that utilize the INTERLEUKIN RECEPTOR COMMON GAMMA SUBUNIT.; A Janus kinase subtype that is predominantly expressed in hematopoietic cells. It is involved in signaling from a broad variety of CYTOKINE RECEPTORS including ones that utilize the INTERLEUKIN RECEPTOR COMMON GAMMA SUBUNIT.;

MeSH synonym : jak3 protein tyrosine kinase; kinase 3, janus; jak-3 protein tyrosine kinase; jak 3 protein tyrosine kinase;

CISMeF synonym : EC 2.7.1.112;

Registry Number MeSH : EC 2.7.10.1; EC 2.7.10.2;

Is substance : O;

UNII : EC 2.7.10.2;

Details

Origin ID

D053616;

UMLS CUI

C0253457;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Tyrosine-Protein Kinase JAK3 [NCIt concept]
Indexing information
- 10,13-dimethyl-17-(2-(6-sulfanylidene-3H-purin-9-yl)acetyl)-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta(a)phenanthren-3-one [MeSH Supplementary Concept]
- 3-(5-(4-(2-hydroxy-2-methylpropionyl)piperazin-1-yl)-2-trifluoromethylphenyl)-4-(1H-indol-3-yl)pyrrole-2,5-dione [MeSH Supplementary Concept]
- PF 956980 [MeSH Supplementary Concept]
- nb-(alpha-hydroxynaphthoyl)serotonin [MeSH Supplementary Concept]
- tofacitinib [MeSH Supplementary Concept]
Record concept(s)
- janus kinase 3 [MeSH concept]
Related MeSH Supplementary Concept(s)
- JAK3 protein, human [MeSH Supplementary Concept]
- Jak3 protein, mouse [MeSH Supplementary Concept]
- Jak3 protein, rat [MeSH Supplementary Concept]
See also
- src homology domains [MeSH Descriptor]
See also inter- (CISMeF)
- Ritlecitinib [NCIt concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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