Syk Kinase - CISMeF

Preferred Label : Syk Kinase;

MeSH definition : An SH2 domain-containing non-receptor tyrosine kinase that regulates signal transduction downstream of a variety of receptors including B-CELL ANTIGEN RECEPTORS. It functions in both INNATE IMMUNITY and ADAPTIVE IMMUNITY and also mediates signaling in CELL ADHESION; OSTEOGENESIS; PLATELET ACTIVATION; and vascular development.;

MeSH synonym : Kinase, Syk; SYK Tyrosine Kinase; Kinase, SYK Tyrosine; Tyrosine Kinase, SYK; Spleen Tyrosine Kinase; Kinase, Spleen Tyrosine; Tyrosine Kinase, Spleen;

Registry Number MeSH : EC 2.7.10.2;

UNII : EC 2.7.10.2;

Details

Origin ID

D000072377;

UMLS CUI

C1698931;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Protein-tyrosine kinase syk [OMIM gene]
- Tyrosine-Protein Kinase SYK [NCIt concept]
Record concept(s)
- syk kinase [MeSH concept]
Related MeSH Supplementary Concept(s)
- SYK protein, human [MeSH Supplementary Concept]
- Syk protein, mouse [MeSH Supplementary Concept]
- Syk protein, rat [MeSH Supplementary Concept]
- Syk protein, zebrafish [MeSH Supplementary Concept]
See also
- src homology domains [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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