protein-tyrosine kinases

Preferred Label : protein-tyrosine kinases;

MeSH definition : Protein kinases that catalyze the PHOSPHORYLATION of TYROSINE residues in proteins with ATP or other nucleotides as phosphate donors.;

MeSH synonym : kinases, protein-tyrosine; tyrosine kinase; tyrosine protein kinase; kinase, tyrosine protein; tyrosine-specific protein kinase; kinase, tyrosine-specific protein; protein kinase, tyrosine-specific; kinases, tyrosine-specific protein; tyrosine specific protein kinases; tyrosylprotein kinase; protein tyrosine kinase; protein kinases, tyrosine; protein-tyrosine kinase; tyrosine protein kinases; protein kinases, tyrosine-specific; kinase, tyrosylprotein; tyrosine-specific protein kinases; kinase, protein-tyrosine; kinase, tyrosine; kinases, tyrosine protein; tyrosine specific protein kinase; protein tyrosine kinases;

CISMeF synonym : EC 2.7.1.112;

MeSH CAS label : ATP:protein-tyrosine O-phosphotransferase;

MeSH Related Number : EC 2.7.10.2;

Registry Number MeSH : EC 2.7.10.1;

Wikipedia link : https://en.wikipedia.org/wiki/Tyrosine protein kinase;

Is substance : O;

UNII : EC 2.7.10.1;

Details

Origin ID

D011505;

UMLS CUI

C0033681;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Fibroblast Growth Factor Receptor 3 [NCIt concept]
- Megakaryocyte-Associated Tyrosine-Protein Kinase [NCIt concept]
- Protein Tyrosine Kinase [NCIt concept]
- Protein-tyrosine kinase (substance) [SNOMED CT concept]
- Proto-Oncogene Tyrosine-Protein Kinase Receptor Ret [NCIt concept]
- Tyrosine-Protein Kinase RYK [NCIt concept]
- megakaryocyte-associated tyrosine kinase [HGNC gene]
- protein-tyrosine kinase [SNOMED Notion]
False automatic mappings
- Combined immunodeficiency due to ZAP70 deficiency [ORDO Disease]
- Ephrin Type-A Receptor 8 [NCIt concept]
Indexing information
- ((dimethylamino)methyl)acrylo-4-((benzoylsulfonyl)oxy)phenone [MeSH Supplementary Concept]
- ((dimethylamino)methyl)acrylo-4-((hydroxybenzoylsulfonyl)oxy)phenone [MeSH Supplementary Concept]
- 1,3-dihydro-5,6-dimethoxy-3-((4-hydroxyphenyl)methylene)-2H-indol-2-one [MeSH Supplementary Concept]
- 10-(4-acetimdobenzylidene)-9-anthrone [MeSH Supplementary Concept]
- 1a-docosahexaenoyl mitomycin C [MeSH Supplementary Concept]
- 2-(4-(2-diethylaminoethoxy)phenylamino)-8-ethyl-6-phenyl-8H-pyrido(2,3-d)pyrimidin-7-one [MeSH Supplementary Concept]
- 2-amino-4-(4'-hydroxyphenyl)-1,1,3-tricyanobuta-1,3-diene [MeSH Supplementary Concept]
- 2-hydroxy-5-(2,5-dihydrobenzyl)aminobenzoic acid [MeSH Supplementary Concept]
- 3'-chloro-5,7-dihydroxyisoflavone [MeSH Supplementary Concept]
- 3,3',4,5'-tetrahydroxystilbene [MeSH Supplementary Concept]
- 3-methoxyl-5-(2-,2-dicyanoethenyl)catechol [MeSH Supplementary Concept]
- 4'-amino-6-hydroxyflavone [MeSH Supplementary Concept]
- 4-((3-bromophenyl)amino)-6-(methylamino)pyrimido(5,4-d)pyrimidine [MeSH Supplementary Concept]
- 4-(3-(hydroxyamino)-3-oxoprop-1-enyl)-N-(4-methyl-3-(4-(pyridin-3-yl)thiazol-2-ylamino)phenyl)benzamide [MeSH Supplementary Concept]
- 4-(3-chloroanilino)quinazoline [MeSH Supplementary Concept]
- 4-tolyloxycarbonyl-2-ethyl adenosine monophosphate [MeSH Supplementary Concept]
- 6-hydroxy-4',5,7-triaminoflavone [MeSH Supplementary Concept]
- 6-methoxy-4',5-dihydroxyflavone-7-O-glucoside [MeSH Supplementary Concept]
- 7,8-dihydroxyisoquinoline-3-carboxamide [MeSH Supplementary Concept]
- AG 127 [MeSH Supplementary Concept]
- AG 183 [MeSH Supplementary Concept]
- AG 30 [MeSH Supplementary Concept]
- AG 372 [MeSH Supplementary Concept]
- AG 494 [MeSH Supplementary Concept]
- AG 556 [MeSH Supplementary Concept]
- AG-879 [MeSH Supplementary Concept]
- AGL 2592 [MeSH Supplementary Concept]
- AKAP13 protein, human [MeSH Supplementary Concept]
- BE 23372M [MeSH Supplementary Concept]
- Bcl2 protein, mouse [MeSH Supplementary Concept]
- CGP 53716 [MeSH Supplementary Concept]
- CH 331 [MeSH Supplementary Concept]
- CL 387785 [MeSH Supplementary Concept]
- CP 127374 [MeSH Supplementary Concept]
- E4 protein, human papillomavirus type 6 [MeSH Supplementary Concept]
- E6 protein, human papillomavirus type 16 [MeSH Supplementary Concept]
- GOLGA5 protein, human [MeSH Supplementary Concept]
- HAJ11 [MeSH Supplementary Concept]
- IBtk protein, human [MeSH Supplementary Concept]
- KB 23 [MeSH Supplementary Concept]
- LFM A13 [MeSH Supplementary Concept]
- MCF2 protein, human [MeSH Supplementary Concept]
- N-(4-((3,4-dichloro-6-fluoro-phenyl)amino)quinazoline-6-yl)-2-chloroacetamide [MeSH Supplementary Concept]
- N-(4-(1-methylethyl)phenyl)-4-(2-(3-pyridinyl)ethyl)-1-phthalazinamine [MeSH Supplementary Concept]
- N-beta-alanyl-5-S-glutathionyl-3,4-dihydroxyphenylalanine [MeSH Supplementary Concept]
- N1-(2-aminophenyl)-N4-(4-methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl)terephthalamide [MeSH Supplementary Concept]
- N2-(2-aminophenyl)-N5-(4-methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl)thiophene-2,5-dicarboxamide [MeSH Supplementary Concept]
- PD 089828 [MeSH Supplementary Concept]
- PD 145709 [MeSH Supplementary Concept]
- PD 161570 [MeSH Supplementary Concept]
- PD 166285 [MeSH Supplementary Concept]
- PD 166866 [MeSH Supplementary Concept]
- PD 173955 [MeSH Supplementary Concept]
- PD 180970 [MeSH Supplementary Concept]
- RG 14467 [MeSH Supplementary Concept]
- RG 14620 [MeSH Supplementary Concept]
- RG 14921 [MeSH Supplementary Concept]
- RIOK1 protein, human [MeSH Supplementary Concept]
- Ros1 protein, mouse [MeSH Supplementary Concept]
- Ros1 protein, rat [MeSH Supplementary Concept]
- ST 271 [MeSH Supplementary Concept]
- ST 638 [MeSH Supplementary Concept]
- SU 4984 [MeSH Supplementary Concept]
- SU 5402 [MeSH Supplementary Concept]
- SU 5768 [MeSH Supplementary Concept]
- Sh2b2 protein, mouse [MeSH Supplementary Concept]
- TKM0150 [MeSH Supplementary Concept]
- TWF2 protein, human [MeSH Supplementary Concept]
- XR774 [MeSH Supplementary Concept]
- ZM 252868 [MeSH Supplementary Concept]
- clavilactone D [MeSH Supplementary Concept]
- desmal [MeSH Supplementary Concept]
- env-sea oncogene protein, avian erythroblastosis retrovirus [MeSH Supplementary Concept]
- erbstatin [MeSH Supplementary Concept]
- ethanimidothioic acid N-((N-butylthio-N-methylamino)-carbonyloxy)-methylester [MeSH Supplementary Concept]
- ethyl 2,5-dihydroxycinnamate [MeSH Supplementary Concept]
- fish protein, mouse [MeSH Supplementary Concept]
- flumatinib [MeSH Supplementary Concept]
- geldanamycin [MeSH Supplementary Concept]
- herbimycin [MeSH Supplementary Concept]
- lavendustin A [MeSH Supplementary Concept]
- lavendustin B [MeSH Supplementary Concept]
- lavendustin C6 [MeSH Supplementary Concept]
- malhamensilipin A [MeSH Supplementary Concept]
- methyl 2,5-dihydroxycinnamate [MeSH Supplementary Concept]
- methyl 7,8-dihydroxyisoquinoline-3-carboxylate [MeSH Supplementary Concept]
- monorden [MeSH Supplementary Concept]
- nilotinib [MeSH Supplementary Concept]
- oncogene protein E2, human papillomavirus type 18 [MeSH Supplementary Concept]
- oncogene protein E4, human papilloma virus type 1 [MeSH Supplementary Concept]
- oncogene protein E4, human papillomavirus type 16 [MeSH Supplementary Concept]
- oncogene protein E4, type 11, human papillomavirus [MeSH Supplementary Concept]
- oncogene protein E5, bovine papillomavirus type 1 [MeSH Supplementary Concept]
- oncogene protein E5, human papillomavirus type 16 [MeSH Supplementary Concept]
- oncogene protein E7, human papillomavirus type 16 [MeSH Supplementary Concept]
- oncogene proteins v-ets [MeSH Supplementary Concept]
- oncoprotein CLTCL-ALK [MeSH Supplementary Concept]
- peptide A [MeSH Supplementary Concept]
- protein E6, bovine papillomavirus [MeSH Supplementary Concept]
- proto-oncogene protein c-myc pp59 [MeSH Supplementary Concept]
- proto-oncogene protein pp60(c-Src) (140-157) [MeSH Supplementary Concept]
- prunetin [MeSH Supplementary Concept]
- raytide [MeSH Supplementary Concept]
- semicochliodinol A [MeSH Supplementary Concept]
- semicochliodinol B [MeSH Supplementary Concept]
- tandutinib [MeSH Supplementary Concept]
- tyrphostin 11 [MeSH Supplementary Concept]
- tyrphostin 25 [MeSH Supplementary Concept]
- tyrphostin 51 [MeSH Supplementary Concept]
- tyrphostin A23 [MeSH Supplementary Concept]
- tyrphostin A46 [MeSH Supplementary Concept]
- tyrphostin AG 1112 [MeSH Supplementary Concept]
- tyrphostin AG 568 [MeSH Supplementary Concept]
- tyrphostin AG34 [MeSH Supplementary Concept]
- tyrphostin AG825 [MeSH Supplementary Concept]
- tyrphostin AG957 [MeSH Supplementary Concept]
- v-ros protein, avian sarcoma virus UR2 [MeSH Supplementary Concept]
- v-ryk protein, avian retrovirus [MeSH Supplementary Concept]
Manual NTBT mappings (CISMeF)
- Combined T and B cell immunodeficiency [ORDO Disease]
Record concept(s)
- Protein-Tyrosine kinases [MeSH concept]
Related MeSH Supplementary Concept(s)
- AATK protein, human [MeSH Supplementary Concept]
- AATK protein, rat [MeSH Supplementary Concept]
- ADK1 protein, arabidopsis [MeSH Supplementary Concept]
- APK1A protein, arabidopsis [MeSH Supplementary Concept]
- ARG tyrosine kinase [MeSH Supplementary Concept]
- Abl protein, Drosophila [MeSH Supplementary Concept]
- BMX protein, human [MeSH Supplementary Concept]
- BTL protein, Drosophila [MeSH Supplementary Concept]
- Btk29A protein, drosophila [MeSH Supplementary Concept]
- CDC42BPB protein, human [MeSH Supplementary Concept]
- Cdc42Hs-associated kinase [MeSH Supplementary Concept]
- CpsD protein, streptococcus pneumoniae [MeSH Supplementary Concept]
- DYRK3 protein, human [MeSH Supplementary Concept]
- DYRK3 protein, mouse [MeSH Supplementary Concept]
- DYRK3 protein, rat [MeSH Supplementary Concept]
- Dyrk1A protein, xenopus [MeSH Supplementary Concept]
- Dyrk1b protein, zebrafish [MeSH Supplementary Concept]
- Dyrk2 protein, zebrafish [MeSH Supplementary Concept]
- FAK-related nonkinase [MeSH Supplementary Concept]
- FRK protein, human [MeSH Supplementary Concept]
- FRK-1 protein, C elegans [MeSH Supplementary Concept]
- HTK16 protein, hydra attenuata [MeSH Supplementary Concept]
- Jak2a protein, zebrafish [MeSH Supplementary Concept]
- Kos1 protein, mouse [MeSH Supplementary Concept]
- Ltk protein, zebrafish [MeSH Supplementary Concept]
- MAN2A1-FER fusion protein, human [MeSH Supplementary Concept]
- MBK-2 protein, C elegans [MeSH Supplementary Concept]
- MYT1 kinase, xenopus [MeSH Supplementary Concept]
- Myt1 kinase, rat [MeSH Supplementary Concept]
- Ntrk2 protein, mouse [MeSH Supplementary Concept]
- Old-2 protein, C elegans [MeSH Supplementary Concept]
- PEAK1 protein, human [MeSH Supplementary Concept]
- PK12 protein, nicotiana tabacum [MeSH Supplementary Concept]
- PKDCC protein, human [MeSH Supplementary Concept]
- PKMYT1 protein, human [MeSH Supplementary Concept]
- PTK6 protein, human [MeSH Supplementary Concept]
- PTK72 [MeSH Supplementary Concept]
- Pkdcc.1 protein, Xenopus [MeSH Supplementary Concept]
- Pkdcc.2 protein, Xenopus [MeSH Supplementary Concept]
- Ptk6 protein, mouse [MeSH Supplementary Concept]
- PtkA protein, Mycobacterium tuberculosis [MeSH Supplementary Concept]
- RB1CC1 protein, human [MeSH Supplementary Concept]
- RET-PTC oncoprotein, rat [MeSH Supplementary Concept]
- ROS1 protein, human [MeSH Supplementary Concept]
- Ret-Ptc1 oncoprotein, mouse [MeSH Supplementary Concept]
- Rop16 protein, toxoplasma gondii [MeSH Supplementary Concept]
- SID-3 protein, C elegans [MeSH Supplementary Concept]
- SWE1 protein, S cerevisiae [MeSH Supplementary Concept]
- Scd-2 protein, C elegans [MeSH Supplementary Concept]
- SksC protein, chlamydomonas reinhardtii [MeSH Supplementary Concept]
- SplA protein, dictyostelium discoideum [MeSH Supplementary Concept]
- Src64B protein, drosophila [MeSH Supplementary Concept]
- TEL-ABL fusion protein, human [MeSH Supplementary Concept]
- TEL-JAK1 protein, human [MeSH Supplementary Concept]
- TEL-JAK3 protein, human [MeSH Supplementary Concept]
- TEL-TYK2 protein, human [MeSH Supplementary Concept]
- TK4 protein, schistosoma mansoni [MeSH Supplementary Concept]
- TNK1 protein, human [MeSH Supplementary Concept]
- TNK2 protein, human [MeSH Supplementary Concept]
- TNNI3K protein, rat [MeSH Supplementary Concept]
- TPA-1 protein, C elegans [MeSH Supplementary Concept]
- TTK protein, human [MeSH Supplementary Concept]
- TWF1 protein, human [MeSH Supplementary Concept]
- TWF2 protein, mouse [MeSH Supplementary Concept]
- Tec29 protein-tyrosine kinase [MeSH Supplementary Concept]
- Tnk2 protein, mouse [MeSH Supplementary Concept]
- Tnk2 protein, rat [MeSH Supplementary Concept]
- WEE1 protein, human [MeSH Supplementary Concept]
- WEE1 protein, xenopus [MeSH Supplementary Concept]
- WZC protein, bacteria [MeSH Supplementary Concept]
- Wee1 protein, drosophila [MeSH Supplementary Concept]
- Wee1 protein, mouse [MeSH Supplementary Concept]
- Wee1 protein, rat [MeSH Supplementary Concept]
- Wee1B protein, mouse [MeSH Supplementary Concept]
- Wee2 protein, human [MeSH Supplementary Concept]
- Wee2 protein, xenopus [MeSH Supplementary Concept]
- aatk protein, mouse [MeSH Supplementary Concept]
- ack protein, drosophila [MeSH Supplementary Concept]
- ack-related tyrosine kinase-1, C elegans [MeSH Supplementary Concept]
- bmx protein, mouse [MeSH Supplementary Concept]
- bmx protein, rat [MeSH Supplementary Concept]
- cdr1 protein, S pombe [MeSH Supplementary Concept]
- clk dual-specificity kinases [MeSH Supplementary Concept]
- csf1ra protein, zebrafish [MeSH Supplementary Concept]
- csf1rb protein, zebrafish [MeSH Supplementary Concept]
- dnt protein, Drosophila [MeSH Supplementary Concept]
- dyrk kinase [MeSH Supplementary Concept]
- emb protein-tyrosine kinase [MeSH Supplementary Concept]
- emt protein-tyrosine kinase [MeSH Supplementary Concept]
- etk protein, E coli [MeSH Supplementary Concept]
- frk protein, mouse [MeSH Supplementary Concept]
- fyk kinase [MeSH Supplementary Concept]
- gtk kinase [MeSH Supplementary Concept]
- hinterteil protein, hydra vulgaris [MeSH Supplementary Concept]
- htl protein, Drosophila [MeSH Supplementary Concept]
- insulin receptor tyrosine kinase [MeSH Supplementary Concept]
- ksy protein, xenopus [MeSH Supplementary Concept]
- lynA protein, rat [MeSH Supplementary Concept]
- lynB protein, rat [MeSH Supplementary Concept]
- matk protein, rat [MeSH Supplementary Concept]
- mik1 protein, S pombe [MeSH Supplementary Concept]
- p80(NPM-ALK) protein [MeSH Supplementary Concept]
- protein tyrosine kinase Pyk2-H [MeSH Supplementary Concept]
- proto-oncogene protein c-fes-fps [MeSH Supplementary Concept]
- receptor protein-tyrosine phosphatase, geodia cydonium [MeSH Supplementary Concept]
- ret-PTC fusion oncoproteins, human [MeSH Supplementary Concept]
- sea protein, gallus gallus [MeSH Supplementary Concept]
- shark protein, drosophila [MeSH Supplementary Concept]
- tec protein, rat [MeSH Supplementary Concept]
- tec protein-tyrosine kinase [MeSH Supplementary Concept]
- tkr-1 protein, C elegans [MeSH Supplementary Concept]
- tropomyosin-related kinase-B, human [MeSH Supplementary Concept]
- ttk protein, zebrafish [MeSH Supplementary Concept]
- tyrosine protein kinase IIB [MeSH Supplementary Concept]
- v-fgr protein, feline sarcoma virus [MeSH Supplementary Concept]
- v-fps oncogene protein, fujinami sarcoma virus [MeSH Supplementary Concept]
- v-yes protein, avian sarcoma virus Y73 [MeSH Supplementary Concept]
- vlk protein, mouse [MeSH Supplementary Concept]
- wee-1.3 protein, C elegans [MeSH Supplementary Concept]
- wee1 protein, S pombe [MeSH Supplementary Concept]
- wzc protein, E coli [MeSH Supplementary Concept]
See also
- oncogene protein pp60(v-src) [MeSH Descriptor]
- src homology domains [MeSH Descriptor]
See also inter- (CISMeF)
- Substance with protein-tyrosine kinase inhibitor mechanism of action (substance) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Protein Tyrosine Kinase [NCIt concept]
- Protein-tyrosine kinase (substance) [SNOMED CT concept]
- protein-tyrosine kinase [SNOMED Notion]

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