Imatinib Mesylate

Preferred Label : Imatinib Mesylate;

MeSH definition : A tyrosine kinase inhibitor and ANTINEOPLASTIC AGENT that inhibits the BCR-ABL kinase created by chromosome rearrangements in CHRONIC MYELOID LEUKEMIA and ACUTE LYMPHOBLASTIC LEUKEMIA, as well as PDG-derived tyrosine kinases that are overexpressed in gastrointestinal stromal tumors.;

MeSH synonym : Mesylate, Imatinib; Imatinib Methanesulfonate; Methanesulfonate, Imatinib;

MeSH Hyperonym : imatinib; Alpha-(4-methyl-1-piperazinyl)-3'-((4-(3-pyridyl)-2-pyrimidinyl)amino)-p-tolu-p-toluidide;

MeSH hyponym : ST 1571; gleevec; CGP 57148; STI571; STI-571; STI 571; Glivec; ST1571; CGP57148B; CGP-57148; CGP57148;

MeSH Related Number : 220127-57-1 (imatinib mesilate); BKJ8M8G5HI;

Wikipedia link : https://en.wikipedia.org/wiki/Imatinib mesylate;

Is substance : O;

UNII : 8A1O1M485B;

Details

Origin ID

D000068877;

UMLS CUI

C0939537;

ATC code(s)
- imatinib [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
CISMeF manual mappings
- Imatinib Mesylate [NCIt concept]
- Imatinib mesilate (substance) [SNOMED CT concept]
Currated CISMeF NLP mapping
- Imatinib mesylate [International Nonproprietary Name]
- Imatinib mesylate [Substance BNPC]
- Imatinib mesylate [LOINC component]
Exact mapping(s) to DCI
- Imatinib mesylate [International Nonproprietary Name]
Pharmacological action(s)
- antineoplastic agents [MeSH Descriptor]
- protein kinase inhibitors [MeSH Descriptor]
Record concept(s)
- CGP 57148 [MeSH concept]
- ST 1571 [MeSH concept]
- STI571 [MeSH concept]
- gleevec [MeSH concept]
- imatinib [MeSH concept]
- imatinib mesylate [MeSH concept]
See also inter- (CISMeF)
- Product containing imatinib (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Imatinib Mesylate [NCIt concept]
- Imatinib mesilate (substance) [SNOMED CT concept]
- Imatinib mesylate [LOINC component]
- Imatinib mesylate [International Nonproprietary Name]
- Imatinib mesylate [Substance BNPC]
Validated automatic mappings to NTBT
- Imatinib [NCIt concept]
- Imatinib (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

Main resources

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