TOR Serine-Threonine kinases

Preferred Label : TOR Serine-Threonine kinases;

MeSH definition : A serine threonine kinase that controls a wide range of growth-related cellular processes. The protein is referred to as the target of RAPAMYCIN due to the discovery that SIROLIMUS (commonly known as rapamycin) forms an inhibitory complex with TACROLIMUS BINDING PROTEIN 1A that blocks the action of its enzymatic activity.;

MeSH synonym : kinases, TOR Serine-Threonine; Serine-Threonine kinases, TOR; FKBP12-Rapamycin associated protein; FKBP12 rapamycin associated protein; FKBP12-Rapamycin Complex-Associated protein; FKBP12 rapamycin complex associated protein; mechanistic target of rapamycin protein; TOR kinases; mTOR Serine-Threonine kinases; kinases, mTOR Serine-Threonine; Serine-Threonine kinases, mTOR; mTOR serine threonine kinases; RAFT-1 protein; protein, RAFT-1; RAFT 1 protein; rapamycin target protein; target of rapamycin proteins; FK506 binding protein 12-Rapamycin associated protein 1; FK506 binding protein 12 rapamycin associated protein 1; mTOR protein; protein, mTOR; TOR serine threonine kinases; Mammalian Target of Rapamycin; Target of Rapamycin Protein; Protein Target, Rapamycin; Rapamycin Protein Target; mTOR Serine-Threonine Kinase; Kinase, mTOR Serine-Threonine; Serine-Threonine Kinase, mTOR; mTOR Serine Threonine Kinase; TOR Kinase; Kinase, TOR; TOR Serine-Threonine Kinase; Kinase, TOR Serine-Threonine; Serine-Threonine Kinase, TOR; TOR Serine Threonine Kinase;

CISMeF synonym : Complex-Associated protein, FKBP12-Rapamycin; associated protein, FKBP12-Rapamycin; protein, FKBP12-Rapamycin Complex-Associated; protein, FKBP12-Rapamycin associated; protein, rapamycin target; rapamycin proteins target; target protein, rapamycin;

Registry Number MeSH : EC 2.7.1.1;

Is substance : O;

UNII : EC 2.7.11.1;

Details

Origin ID

D058570;

UMLS CUI

C0293060;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Indexing information
- RPTOR protein, human [MeSH Supplementary Concept]
- Rptor protein, mouse [MeSH Supplementary Concept]
- antrocin [MeSH Supplementary Concept]
- rptor protein, rat [MeSH Supplementary Concept]
Record concept(s)
- TOR Serine-Threonine kinases [MeSH concept]
Related MeSH Supplementary Concept(s)
- DEPTOR protein, human [MeSH Supplementary Concept]
- MTOR protein, human [MeSH Supplementary Concept]
- mTOR protein, mouse [MeSH Supplementary Concept]
- mTOR protein, rat [MeSH Supplementary Concept]
- mTOR protein, zebrafish [MeSH Supplementary Concept]
- target of rapamycin protein, drosophila [MeSH Supplementary Concept]
See also
- MTOR Inhibitors [MeSH Descriptor]
See also (suggested by CISMeF)
- Everolimus [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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