tyrphostin A23

Preferred Label : tyrphostin A23;

MeSH note : inhibits EGF-stimulated thymidine incorporation as well as EGF-stimulated receptor autophosphorylation & tyrosine phosphorylation & cell proliferation; structure given in first source;

CISMeF synonym : AG 18; AG-18; RG 50810; tyrphostin A1;

MeSH synonym : (3,4-dihydroxybenzylidene)malononitrile; 3,4-dihydroxybenzylidenemalononitrile; (3,4-dihydroxyphenyl)methylene propanedinitrile; tyrphostin 23; tyrphostin AG18; tyrphostin RG50810;

MeSH hyponym : RG-50810;

MeSH Related Number : 118409-57-7 (tyrphostin 23);

Registry Number MeSH : 118409-57-7;

Is substance : O;

UNII : RV0GCD31OJ;

Details

Origin ID

C060641;

UMLS CUI

C0638102;

Automatic exact mappings (from CISMeF team)
- Tyrphostin A1 [NCIt concept]
Currated CISMeF NLP mapping
- Tyrphostin A23 [NCIt concept]
MeSH indexing information
- protein-tyrosine kinases [MeSH Descriptor]
MeSH term(s) associated for indexing
- tyrphostins [MeSH Descriptor]
Pharmacological action(s)
- antineoplastic agents [MeSH Descriptor]
- enzyme inhibitors [MeSH Descriptor]
Record concept(s)
- RG 50810 [MeSH concept]
- tyrphostin A1 [MeSH concept]
- tyrphostin A23 [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Tyrphostin A23 [NCIt concept]

Keyword's position in hierarchy(ies) :

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