" /> oncogene protein pp60(v-src) - CISMeF





Preferred Label : oncogene protein pp60(v-src);

MeSH definition : A tyrosine-specific protein kinase encoded by the v-src oncogene of ROUS SARCOMA VIRUS. The transforming activity of pp60(v-src) depends on both the lack of a critical carboxy-terminal tyrosine phosphorylation site at position 527, and the attachment of pp60(v-src) to the plasma membrane which is accomplished by myristylation of its N-terminal glycine.;

MeSH synonym : oncogene protein src; src, oncogene protein; v src protein pp60; avian sarcoma virus transforming protein; pp60 v src; protein src, oncogene; pp60 v-src; src oncogene protein pp60; oncogene protein pp60(src); p60(v-src); phosphoprotein pp60(v-src); v-src, pp60; rous sarcoma virus-transforming protein pp60(v-src); src oncogene product pp60; v-src protein; v src protein; v-src protein pp60; protein pp60, v-src; pp60, v-src protein; avian sarcoma virus-transforming protein; pp60(v-src);

CISMeF synonym : EC 2.7.1.112;

MeSH CAS label : kinase (phosphorylating), protein pp60src;

Registry Number MeSH : EC 2.7.10.2;

Is substance : O;

UNII : EC 2.7.10.2;

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A tyrosine-specific protein kinase encoded by the v-src oncogene of ROUS SARCOMA VIRUS. The transforming activity of pp60(v-src) depends on both the lack of a critical carboxy-terminal tyrosine phosphorylation site at position 527, and the attachment of pp60(v-src) to the plasma membrane which is accomplished by myristylation of its N-terminal glycine.

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28/04/2025


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