Tyrosine-Protein Kinase Yes

Preferred Label : Tyrosine-Protein Kinase Yes;

NCIt synonyms : c-yes Kinase; YES1; YES1 Protein Tyrosine Kinase; p61-YES; EC 2.7.10.2; Proto-Oncogene c-Yes;

NCIt definition : Tyrosine-protein kinase Yes (543 aa, 61 kDa) is encoded by the human YES1 gene. This protein plays a role in both receptor tyrosine kinase-mediated signaling and tyrosine phosphorylation.;

Détails

Origin ID

C18556;

UMLS CUI

C1452531;

OMIM relation
- V-yes-1 yamaguchi sarcoma viral oncogene [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- YES1 protein, human [MeSH concept]
- YES1 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Kinase Family Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- SRC Family Gene [NCIt concept]
- Transferase Gene [NCIt concept]
- YES1 Gene [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- SH2 Domain [NCIt concept]
- SH3 Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
- Tyrosine Kinase Domain [NCIt concept]
gene_product_is_element_in_pathway
- Adherens Junction Assembly Pathway [NCIt concept]
- Noncanonical Wnt Signaling Pathway [NCIt concept]
- Tight Junction Assembly Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Differentiation Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Proliferation [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Signal Transduction [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]
is_target
- SRC/YES1 Kinase Inhibitor NXP900 [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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