Tyrosine-Protein Kinase Blk

Preferred Label : Tyrosine-Protein Kinase Blk;

NCIt synonyms : p55-BLK; p55-BLK Kinase; BLK Nonreceptor Tyrosine Kinase; B Lymphocyte Kinase; B Lymphoid Tyrosine Kinase; EC 2.7.10.2;

NCIt definition : Tyrosine-protein kinase Blk (505 aa, 58 kDa) is encoded by the human BLK gene. This protein is involved in protein phosphorylation and B-cell receptor signaling.;

Details

Origin ID

C17697;

UMLS CUI

C3713783;

OMIM relation
- Blk protooncogene, src family tyrosine kinase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- BLK protein, human [MeSH concept]
- BLK protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- BLK Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Kinase Family Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- SRC Family Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- SH2 Domain [NCIt concept]
- SH3 Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
- Tyrosine Kinase Domain [NCIt concept]
gene_product_is_element_in_pathway
- Alpha-Synuclein Signaling Pathway [NCIt concept]
- AlphaM/Beta2 Integrin Signaling Pathway [NCIt concept]
- Class I PI3K Signaling Pathway [NCIt concept]
- Ephrin A Forward Signaling Pathway [NCIt concept]
- Ephrin B Reverse Signaling Pathway [NCIt concept]
- Glypican 1 Signaling Pathway [NCIt concept]
- PDGFR-beta Signaling Pathway [NCIt concept]
- PTPN1 Signaling Pathway [NCIt concept]
- Regulation of p38-alpha and p38-beta Pathway [NCIt concept]
- Thromboxane A2 Receptor Family Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- B-Cell Activation [NCIt concept]
- Cell Differentiation Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Proliferation [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Signal Transduction [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]

Keyword's position in hierarchy(ies) :

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