GRB2-Related Adapter Protein

Preferred Label : GRB2-Related Adapter Protein;

NCIt synonyms : GRAP; GRB2-Related Adaptor Protein; Growth Factor Receptor-Bound Protein 2-Related Adaptor Protein;

NCIt definition : GRB2-related adapter protein (217 aa, 25 kDa) is encoded by the human GRAP gene. This protein is involved in coupling receptor tyrosine kinases to downstream Ras family signaling pathways.;

Details

Origin ID

C26221;

UMLS CUI

C1722062;

Automatic exact mappings (from CISMeF team)
- GRB2 related adaptor protein [ORDO Gene]
- Grb2-related adaptor protein [OMIM gene]
OMIM relation
- Grb2-related adaptor protein [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- grap protein, human [MeSH Supplementary Concept]
- grap protein, human [MeSH concept]
gene_encodes_gene_product
- Adaptor Signaling Protein Gene [NCIt concept]
- GRAP Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_expressed_in_tissue
- Lymphoid Tissue [NCIt concept]
gene_product_has_structural_domain_or_motif
- SH2 Domain [NCIt concept]
- SH3 Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Protein-Protein Interaction [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients