Suppressor of Cytokine Signaling 2

Preferred Label : Suppressor of Cytokine Signaling 2;

NCIt synonyms : SSI-2; STAT-Induced STAT Inhibitor-2; SOCS-2; CIS-2; STAT-Induced STAT Inhibitor 2; STAT Induced STAT Inhibitor-2; Suppressor of Cytokine Signaling-2; Cytokine-Inducible SH2 Protein 2;

NCIt definition : Suppressor of cytokine signaling 2 (198 aa, 22 kDa) is encoded by the human SOCS2 gene. This protein is involved in the modulation of cytokine signaling.;

Details

Origin ID

C116027;

UMLS CUI

C0540340;

Automatic exact mappings (from CISMeF team)
- SHOC2 leucine rich repeat scaffold protein [ORDO Gene]
- Suppressor of cytokine signaling 2 [OMIM gene]
- suppressor of cytokine signaling 2 [HGNC gene]
OMIM relation
- Suppressor of cytokine signaling 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- SOCS2 protein, human [MeSH Supplementary Concept]
- SOCS2 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- SOCS2 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
- Suppressor of Cytokine Signaling Family Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytosol [NCIt concept]
gene_product_has_structural_domain_or_motif
- SH2 Domain [NCIt concept]
- SOCS Box Domain [NCIt concept]
gene_product_is_element_in_pathway
- IL2-Mediated Signaling Pathway [NCIt concept]
- Insulin/Insulin Receptor Signaling Pathway [NCIt concept]
- Jak-STAT Signaling Pathway [NCIt concept]
- Type II Diabetes Mellitus Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cytokine Signaling [NCIt concept]
- Negative Regulation of Apoptosis [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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