Suppressor of Cytokine Signaling 3

Preferred Label : Suppressor of Cytokine Signaling 3;

NCIt synonyms : CIS-3; Cytokine-Inducible SH2 Protein 3; SOCS-3; SSI-3; STAT-Induced STAT Inhibitor 3;

NCIt definition : Suppressor of cytokine signaling 3 (225 aa, 25 kDa) is encoded by the human SOCS3 gene. This protein is involved in the down-regulation of cytokine-stimulated signaling.;

Details

Origin ID

C97975;

UMLS CUI

C3275257;

OMIM relation
- Suppressor of cytokine signaling 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- SOCS3 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
- Suppressor of Cytokine Signaling Family Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytosol [NCIt concept]
gene_product_has_structural_domain_or_motif
- SH2 Domain [NCIt concept]
- SOCS Box Domain [NCIt concept]
gene_product_is_element_in_pathway
- ATF-2 Transcription Factor Signaling Pathway [NCIt concept]
- Adipocytokine Signaling Pathway [NCIt concept]
- Erythropoietin Signaling Pathway [NCIt concept]
- IL2-Mediated Signaling Pathway [NCIt concept]
- IL22 Signaling Pathway [NCIt concept]
- IL23-Mediated Signaling Pathway [NCIt concept]
- IL2RB Pathway [NCIt concept]
- IL4-Mediated Signaling Pathway [NCIt concept]
- IL6-Mediated Signaling Pathway [NCIt concept]
- Insulin/Insulin Receptor Signaling Pathway [NCIt concept]
- Jak-STAT Signaling Pathway [NCIt concept]
- PTPN1 Signaling Pathway [NCIt concept]
- Type II Diabetes Mellitus Pathway [NCIt concept]
- Ubiquitin-mediated Proteolysis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cytokine Signaling [NCIt concept]
- Generalized Growth [NCIt concept]
- Interferon Signaling Process [NCIt concept]
- Negative Regulation of Apoptosis [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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