Ras GTPase-Activating Protein 1

Preferred Label : Ras GTPase-Activating Protein 1;

NCIt synonyms : GAP; p120GAP; Ras p21 Protein Activator; GTPase-Activating Protein; RasGAP; RASA1; p120 RASGAP; Guanosine Triphosphatase-Activating Protein; p120 RAS GTPase Activating Protein;

NCIt definition : Ras GTPase-activating protein 1 (1047 aa, 116 kDa) is encoded by the human RASA1 gene. This protein is involved in the regulation of Ras family GTPases.;

Details

Origin ID

C91777;

UMLS CUI

C2984553;

Automatic exact mappings (from CISMeF team)
- RAS p21 protein activator 1 [HGNC gene]
- section gap [Radlex concept]
OMIM relation
- Ras p21 protein activator 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
Validated automatic mappings to NTBT
- GTPase-Activating proteins [MeSH concept]
- GTPase-activating proteins [MeSH Descriptor]
- ras GTPase-Activating proteins [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- RASA1 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- C2 Domain [NCIt concept]
- PH Domain [NCIt concept]
- SH2 Domain [NCIt concept]
- SH3 Domain [NCIt concept]
gene_product_is_element_in_pathway
- Angiopoietin-1 Receptor Signaling Pathway [NCIt concept]
- Aurora A Signaling Pathway [NCIt concept]
- Aurora B Signaling Pathway [NCIt concept]
- Axon Guidance Pathway [NCIt concept]
- BCR Immune Response Signaling Pathway [NCIt concept]
- EGF Signaling Pathway [NCIt concept]
- Ephrin B Forward Signaling Pathway [NCIt concept]
- Fc-Epsilon Receptor I Signaling Pathway PID [NCIt concept]
- IGF-1 Signaling Pathway [NCIt concept]
- IL2-Mediated Signaling Pathway [NCIt concept]
- Insulin Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- Neurotrophic Factor-Mediated NTRK1 Signaling Pathway [NCIt concept]
- PDGF Signaling Pathway [NCIt concept]
- PDGFR-beta Signaling Pathway [NCIt concept]
- Sprouty Regulation of Tyrosine Kinase Signaling Pathway [NCIt concept]
- Syndecan-2-Mediated Signaling Pathway [NCIt concept]
- TPO Signaling Pathway [NCIt concept]
- VEGFR1 Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Negative Regulation of Apoptosis [NCIt concept]
- Negative Regulation of Cell-Matrix Adhesion [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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