Phosphatidylinositol 3,4,5-Trisphosphate 5-Phosphatase 2

Preferred Label : Phosphatidylinositol 3,4,5-Trisphosphate 5-Phosphatase 2;

NCIt synonyms : SH2-Containing Inositol Phosphatase 2; SH2 Domain-Containing Inositol 5'-Phosphatase 2; INPPL1; EC 3.1.3.8.6; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatase 2; SH2 Domain-Containing Inositol-5'-Phosphatase 2; SH2 Domain-Containing Inositol Phosphatase 2; SHIP-2; Inositol Polyphosphate Phosphatase-Like Protein 1; 51C Protein; Protein 51C; INPPL-1;

NCIt definition : Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 (1258 aa, 139 kDa) is encoded by the human INPPL1 gene. This protein plays a role in the removal of the phosphate in position 5 of phosphatidylinositol-3,4,5-trisphosphate.;

Details

Origin ID

C170416;

UMLS CUI

C5401250;

OMIM relation
- Inositol polyphosphate-4-phosphatase, type I, 107-kd [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- INPPL1 Gene [NCIt concept]
- Phosphatase Family Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytosol [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Proline-Rich Domain [NCIt concept]
- SAM Domain [NCIt concept]
- SH2 Domain [NCIt concept]
- SH3-Binding Motif [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- B Cell Receptor Signaling Pathway [NCIt concept]
- Class I PI3K Signaling Pathway [NCIt concept]
- Ephrin A2 Forward Signaling Pathway [NCIt concept]
- Fc Gamma Receptor-Mediated Phagocytosis Pathway [NCIt concept]
- Inositol Phosphate Metabolism Pathway [NCIt concept]
- Insulin/Insulin Receptor Signaling Pathway [NCIt concept]
- Phosphatidylinositol Signaling System Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Dephosphorylation [NCIt concept]
- Hydrolysis [NCIt concept]
- Phospholipid Metabolism [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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