Tyrosine-Protein Kinase Fgr

Preferred Label : Tyrosine-Protein Kinase Fgr;

NCIt synonyms : FGR; c-FGR Protein; p58c-Fgr; Proto-Oncogene c-Fgr; EC 2.7.10.2; p58-Fgr; Gardner-Rasheed Feline Sarcoma Viral (v-fgr) Oncogene Homolog; p55-FGR;

NCIt definition : Tyrosine-protein kinase Fgr (529 aa, 59 kDa) is encoded by the human FGR gene. This protein plays a role in both tyrosine phosphorylation and receptor-mediated signaling.;

Details

Origin ID

C17483;

UMLS CUI

C1429388;

OMIM relation
- Fgr protooncogene, src family tyrosine kinase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- FGR protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- FGR Gene [NCIt concept]
- Kinase Family Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- SRC Family Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- SH2 Domain [NCIt concept]
- SH3 Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
- Tyrosine Kinase Domain [NCIt concept]
gene_product_is_element_in_pathway
- Chemokine Signaling Pathway [NCIt concept]
- GPCR Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Differentiation Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Proliferation [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Signal Transduction [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]
is_target
- Rebastinib [NCIt concept]
- Rebastinib Tosylate [NCIt concept]

Keyword's position in hierarchy(ies) :

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