SHC-Transforming Protein 2

Preferred Label : SHC-Transforming Protein 2;

NCIt synonyms : Src Homology 2 Domain Containing Transforming Protein 2; SHC2; SHCB; SCK; SLI; Neuronal SHC Adaptor Homolog; SHC-Like Protein SCK; Src Homology 2 Domain-Containing-Transforming Protein C2; SH2 Domain Protein C2; SHC-Transforming Protein B; SHC Transforming Protein 2; Neuronal-SHC Adaptor Homolog Protein; Protein Sck;

NCIt definition : SHC-transforming protein 2 (582 aa, 62 kDa) is encoded by the human SHC2 gene. This protein plays a role in the transduction of signals from activated growth factor receptors to their signaling pathways.;

Details

Origin ID

C29978;

UMLS CUI

C1438152;

Currated CISMeF NLP mapping
- src homology 2 Domain-Containing, transforming protein 2 [MeSH concept]
OMIM relation
- Shc transforming protein 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- SHC2 protein, human [MeSH concept]
- SHC2 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Adaptor Signaling Protein Gene [NCIt concept]
- SHC2 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- PTB Domain [NCIt concept]
- SH2 Domain [NCIt concept]
gene_product_is_element_in_pathway
- Bacterial Invasion of Epithelial Cell Pathway [NCIt concept]
- Chemokine Signaling Pathway [NCIt concept]
- Chronic Myeloid Leukemia Pathway [NCIt concept]
- ERBB Family Signaling Pathway [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
- Glioblastoma Multiforme Pathway [NCIt concept]
- Insulin/Insulin Receptor Signaling Pathway [NCIt concept]
- Natural Killer Cell-Mediated Cytotoxicity Pathway [NCIt concept]
- Neurotrophic Factor-Mediated NTRK1 Signaling Pathway [NCIt concept]
- Neurotrophin Signaling Pathway [NCIt concept]
- VEGF Signaling Pathway [NCIt concept]
- VEGFR1 Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Protein-Protein Interaction [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]

Keyword's position in hierarchy(ies) :

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