" /> Mothers Against Decapentaplegic Homolog 7 - CISMeF





Preferred Label : Mothers Against Decapentaplegic Homolog 7;

NCIt synonyms : SMA- and MAD-Related Protein 7; Mothers Against Decapentaplegic Homolog 7 Protein; Mothers Against DPP Homolog 7 Protein; Mothers Against Decapentaplegic, Drosophila, Homolog 7 Protein; hSMAD7; MAD (Mothers Against Decapentaplegic, Drosophila) Homolog 7 Protein; MADH7; Smad7; SMAD7 Protein; Mothers Against Decapentaplegic Homolog 8; SMAD 7; Mothers Against DPP Homolog 7; Mothers Against DPP Homolog 8; MAD Homolog 8; MAD Homolog 7;

NCIt definition : Mothers against decapentaplegic homolog 7 (426 aa, 46 kDa) is encoded by the human SMAD7 gene. This protein plays a role in the attenuation of transforming growth factor-beta type-1 receptor signal transduction.;

NCIt note : Mothers against decapentaplegic homolog 7 (SMAD7) is a nuclear protein that translocates to the cytoplasm after binding to the E3 ubiquitin ligase SMURF2. In the cytoplasm, this complex catalyzes the ubiquitination and promotes the subsequent degradation of both TGF-beta receptor type-1 and SMAD7.;

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30/07/2025


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