PRKCE wt Allele

Preferred Label : PRKCE wt Allele;

NCIt synonyms : Protein Kinase C, Epsilon wt Allele; nPKC-Epsilon; PKCE;

NCIt definition : Human PRKCE wild-type allele is located in the vicinity of 2p21 and is approximately 537 kb in length. This allele, which encodes protein kinase C epsilon type protein, is involved in diacylglycerol-dependent protein phosphorylation and signal transduction.;

NCIt note : There is a report of a chromosomal aberration involving the MBOAT2 gene and the PRKCE gene, which is associated with breast cancer. (COSMIC);

GenBank Accession Number : NM_005400;

Details

Origin ID

C114338;

UMLS CUI

C3811758;

Automatic exact mappings (from CISMeF team)
- Protein kinase C, epsilon [OMIM gene]
- calcium-independent protein kinase C [MeSH Supplementary Concept]
- nPKC-epsilon [MeSH concept]
- protein kinase C activity [GO term]
OMIM relation
- Protein kinase C, epsilon [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 2p21 [NCIt concept]
gene_is_element_in_pathway
- Centrosome Pathway [NCIt concept]
- Downstream Signaling Pathway in Naive CD8+ T Cells [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway KEGG [NCIt concept]
- Fc Gamma Receptor-Mediated Phagocytosis Pathway [NCIt concept]
- Flumazenil Cardioprotection Pathway [NCIt concept]
- IL2-Mediated Signaling Pathway [NCIt concept]
- Lysophosphatidic Acid Receptor 4 Signaling Pathway [NCIt concept]
- PDGFR-beta Signaling Pathway [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD4+ T Cells [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD8+ T Cells [NCIt concept]
- Tight Junction Assembly Pathway [NCIt concept]
- Type II Diabetes Mellitus Pathway [NCIt concept]
- Vascular Smooth Muscle Contraction Pathway [NCIt concept]
gene_plays_role_in_process
- Apoptosis [NCIt concept]
- Cell Proliferation Regulatory Process [NCIt concept]
- Immune System Process [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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