Vascular Smooth Muscle Contraction Pathway

Preferred Label : Vascular Smooth Muscle Contraction Pathway;

NCIt related terms : Vascular smooth muscle contraction;

Alternative definition : KEGG: The vascular smooth muscle cell (VSMC) is a highly specialized cell whose principal function is contraction. On contraction, VSMCs shorten, thereby decreasing the diameter of a blood vessel to regulate the blood flow and pressure.;

NCI Metathesaurus CUI : CL422172;

KEGG ID : hsa04270;

Details

Origin ID

C91523;

UMLS CUI

C2265839;

Automatic exact mappings (from CISMeF team)
- vascular smooth muscle contraction [GO term]
Semantic type(s)
- Organ or Tissue Function [UMLS semantic type]
UMLS correspondences (same concept)
- vascular smooth muscle contraction [GO term]
has_gene_product_element
- 1-Phosphatidylinositol 4,5-Bisphosphate Phosphodiesterase Beta-3 [NCIt concept]
- 1-Phosphatidylinositol 4,5-Bisphosphate Phosphodiesterase Beta-4 [NCIt concept]
- 85 kDa Calcium-Independent Phospholipase A2 [NCIt concept]
- ADM [NCIt concept]
- Actin, Aortic Smooth Muscle [NCIt concept]
- Actin, Gamma-Enteric Smooth Muscle [NCIt concept]
- Adenosine Receptor A2a [NCIt concept]
- Adenylate Cyclase Type 9 [NCIt concept]
- Alpha-1A Adrenergic Receptor [NCIt concept]
- Alpha-1B Adrenergic Receptor [NCIt concept]
- Atrial Natriuretic Peptide Receptor 1 [NCIt concept]
- Atrial Natriuretic Peptide Receptor 2 [NCIt concept]
- Calcium-Activated Potassium Channel Subunit Alpha-1 [NCIt concept]
- Caldesmon [NCIt concept]
- Calmodulin [NCIt concept]
- Cytosolic Phospholipase A2 [NCIt concept]
- Cytosolic Phospholipase A2 Beta [NCIt concept]
- Dual Specificity Mitogen-Activated Protein Kinase Kinase 1 [NCIt concept]
- Dual Specificity Mitogen-Activated Protein Kinase Kinase 2 [NCIt concept]
- Endothelin-1 Receptor [NCIt concept]
- Guanine Nucleotide-Binding Protein Subunit Alpha-12 [NCIt concept]
- Guanine Nucleotide-Binding Protein Subunit Alpha-13 [NCIt concept]
- Guanylate Cyclase Soluble Subunit Alpha-1 [NCIt concept]
- Guanylate Cyclase Soluble Subunit Alpha-2 [NCIt concept]
- Guanylate Cyclase Soluble Subunit Beta-1 [NCIt concept]
- Inositol 1,4,5-Triphosphate Receptor Associated 1 [NCIt concept]
- Inositol 1,4,5-Trisphosphate Receptor Type 1 [NCIt concept]
- Inositol 1,4,5-Trisphosphate Receptor Type 2 [NCIt concept]
- Mitogen-Activated Protein Kinase 1 [NCIt concept]
- Mitogen-Activated Protein Kinase 3 [NCIt concept]
- Myosin Light Chain Kinase, Smooth Muscle [NCIt concept]
- Myosin-11 [NCIt concept]
- Phospholipase A2 [NCIt concept]
- Phospholipase A2, Membrane Associated [NCIt concept]
- Protein Kinase C Alpha Type [NCIt concept]
- Protein Kinase C Beta Type [NCIt concept]
- Protein Kinase C Delta Type [NCIt concept]
- Protein Kinase C Epsilon Type [NCIt concept]
- Receptor Activity-Modifying Protein 1 [NCIt concept]
- Receptor Activity-Modifying Protein 2 [NCIt concept]
- Rho Guanine Nucleotide Exchange Factor 1 [NCIt concept]
- Rho Guanine Nucleotide Exchange Factor 12 [NCIt concept]
- Rho-Associated Protein Kinase 1 [NCIt concept]
- Rho-Associated Protein Kinase 2 [NCIt concept]
- Serine/Threonine-Protein Kinase A-Raf [NCIt concept]
- Serine/Threonine-Protein Kinase B-Raf [NCIt concept]
- Serine/Threonine-Protein Phosphatase PP1-Alpha Catalytic Subunit [NCIt concept]
- Serine/Threonine-Protein Phosphatase PP1-Beta Catalytic Subunit [NCIt concept]
- Type-1 Angiotensin II Receptor [NCIt concept]
- Vasopressin V1A Receptor [NCIt concept]
- Vasopressin V1B Receptor [NCIt concept]
- Voltage-Dependent L-Type Calcium Channel Subunit Alpha-1C [NCIt concept]
- Voltage-Dependent L-Type Calcium Channel Subunit Alpha-1D [NCIt concept]
- Voltage-Dependent L-Type Calcium Channel Subunit Alpha-1S [NCIt concept]
- cAMP-Dependent Protein Kinase Catalytic Subunit Alpha [NCIt concept]
- cAMP-Dependent Protein Kinase Catalytic Subunit Beta [NCIt concept]
- cAMP-Dependent Protein Kinase Catalytic Subunit Gamma [NCIt concept]
- cGMP-Dependent Protein Kinase 1 [NCIt concept]
pathway_has_gene_element
- ACTA2 wt Allele [NCIt concept]
- ACTG2 wt Allele [NCIt concept]
- ADCY9 wt Allele [NCIt concept]
- ADM wt Allele [NCIt concept]
- ADORA2A wt Allele [NCIt concept]
- ADORA2B wt Allele [NCIt concept]
- ADRA1A wt Allele [NCIt concept]
- ADRA1B wt Allele [NCIt concept]
- AGTR1 wt Allele [NCIt concept]
- ARAF wt Allele [NCIt concept]
- ARHGEF1 wt Allele [NCIt concept]
- ARHGEF12 wt Allele [NCIt concept]
- AVPR1A wt Allele [NCIt concept]
- AVPR1B wt Allele [NCIt concept]
- BRAF wt Allele [NCIt concept]
- CACNA1C wt Allele [NCIt concept]
- CACNA1D wt Allele [NCIt concept]
- CACNA1S wt Allele [NCIt concept]
- CALD1 wt Allele [NCIt concept]
- CALM1 wt Allele [NCIt concept]
- EDNRA wt Allele [NCIt concept]
- GNA12 wt Allele [NCIt concept]
- GNA13 wt Allele [NCIt concept]
- GUCY1A1 wt Allele [NCIt concept]
- GUCY1A2 wt Allele [NCIt concept]
- GUCY1B1 wt Allele [NCIt concept]
- IRAG1 wt Allele [NCIt concept]
- ITPR1 wt Allele [NCIt concept]
- ITPR2 wt Allele [NCIt concept]
- KCNMA1 wt Allele [NCIt concept]
- MAP2K1 wt Allele [NCIt concept]
- MAP2K2 wt Allele [NCIt concept]
- MAPK1 wt Allele [NCIt concept]
- MAPK3 wt Allele [NCIt concept]
- MYH11 wt Allele [NCIt concept]
- MYLK wt Allele [NCIt concept]
- NPR1 wt Allele [NCIt concept]
- NPR2 wt Allele [NCIt concept]
- PLA2G1B wt Allele [NCIt concept]
- PLA2G2A wt Allele [NCIt concept]
- PLA2G4A wt Allele [NCIt concept]
- PLA2G4B wt Allele [NCIt concept]
- PLA2G6 wt Allele [NCIt concept]
- PLCB3 wt Allele [NCIt concept]
- PLCB4 wt Allele [NCIt concept]
- PPP1CA wt Allele [NCIt concept]
- PPP1CB wt Allele [NCIt concept]
- PRKACA wt Allele [NCIt concept]
- PRKACB wt Allele [NCIt concept]
- PRKACG wt Allele [NCIt concept]
- PRKCA wt Allele [NCIt concept]
- PRKCB wt Allele [NCIt concept]
- PRKCD wt Allele [NCIt concept]
- PRKCE wt Allele [NCIt concept]
- PRKG1 wt Allele [NCIt concept]
- RAMP1 wt Allele [NCIt concept]
- RAMP2 wt Allele [NCIt concept]
- ROCK1 wt Allele [NCIt concept]
- ROCK2 wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

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