Programmed Cell Death Protein 1

Preferred Label : Programmed Cell Death Protein 1;

NCIt synonyms : CD279; CD279 Antigen; hPD-1; Protein PD-1; Antigen CD279; PDCD1; PD1;

CISMeF acronym : PDCD1;

NCIt definition : Programmed cell death protein 1 (288 aa, 32 kDa) is encoded by the human PDCD1 gene. This protein is involved in the regulation of apoptosis.;

Details

Origin ID

C94697;

UMLS CUI

C0135710;

Currated CISMeF NLP mapping
- PDCD1 protein, human [MeSH concept]
- PDCD1 protein, human [MeSH Supplementary Concept]
OMIM relation
- Programmed cell death 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- PDCD1 protein, human [MeSH concept]
- PDCD1 protein, human [MeSH Supplementary Concept]
- programmed cell death 1 receptor [MeSH concept]
- programmed cell death 1 receptor [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Apoptosis Regulation Gene [NCIt concept]
- PDCD1 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Apoptosis Regulator [NCIt concept]
- Regulatory Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Immunoglobulin-Like V-Type Domain [NCIt concept]
gene_product_is_element_in_pathway
- Cell Adhesion Molecule Signaling Pathway [NCIt concept]
- T Cell Receptor Signaling Pathway KEGG [NCIt concept]
gene_product_malfunction_associated_with_disease
- Systemic Lupus Erythematosus [NCIt concept]
gene_product_plays_role_in_biological_process
- Apoptosis [NCIt concept]
- Humoral Immunity [NCIt concept]
is_target
- ARC Fusion Protein SL-279252 [NCIt concept]
- Alpha-PD1/IL2 Fusion Protein AWT020 [NCIt concept]
- Anti-HER2/Anti-PD-1 Bispecific Antibody SSGJ-705 [NCIt concept]
- Anti-LAG-3/PD-1 Bispecific Antibody INCA32459 [NCIt concept]
- Anti-PD-1 Antibody AI-025/Anti-CTLA-4 Antibody ONC-392 Combination Formulation AI-061 [NCIt concept]
- Anti-PD-1 Fusion Protein AMP-224 [NCIt concept]
- Anti-PD-1 Monoclonal Antibody 609A [NCIt concept]
- Anti-PD-1 Monoclonal Antibody BAT1306 [NCIt concept]
- Anti-PD-1 Monoclonal Antibody BAT1308 [NCIt concept]
- Anti-PD-1 Monoclonal Antibody GNR-051 [NCIt concept]
- Anti-PD-1 Monoclonal Antibody MEDI0680 [NCIt concept]
- Anti-PD-1 Monoclonal Antibody MW11 [NCIt concept]
- Anti-PD-1 Monoclonal Antibody OSE-279 [NCIt concept]
- Anti-PD-1 Monoclonal Antibody PE0105 [NCIt concept]
- Anti-PD-1 Monoclonal Antibody QL1604 [NCIt concept]
- Anti-PD-1 Monoclonal Antibody SHR-1901 [NCIt concept]
- Anti-PD-1 Monoclonal Antibody SYN125 [NCIt concept]
- Anti-PD-1 Monoclonal Antibody Sym021 [NCIt concept]
- Anti-PD-1 Monoclonal Antibody TY101 [NCIt concept]
- Anti-PD-1/Anti-4-1BB Bispecific Antibody IBI-319 [NCIt concept]
- Anti-PD-1/Anti-CD3 Bispecific Antibody ONO-4685 [NCIt concept]
- Anti-PD-1/Anti-ILT4 Bispecific Antibody CDX-585 [NCIt concept]
- Anti-PD-1/Anti-TGF-beta Bifunctional Fusion Protein TQB2868 [NCIt concept]
- Anti-PD-1/Anti-TGFbRII Bispecific Antibody INCA33890 [NCIt concept]
- Anti-PD-1/Anti-TIGIT Bispecific Antibody IBI321 [NCIt concept]
- Anti-PD-1/Anti-TIM-3 Bispecific Antibody AZD7789 [NCIt concept]
- Anti-PD-1/Anti-TIM-3 Bispecific Antibody LB1410 [NCIt concept]
- Anti-PD-1/Anti-VEGF Bispecific Antibody JS207 [NCIt concept]
- Anti-PD-1/IL-2 Bispecific Antibody Fusion Protein IBI363 [NCIt concept]
- Anti-PD-1/LAG-3 Bispecific Antibody AK129 [NCIt concept]
- Anti-PD-1/LAG-3 Bispecific Antibody EMB-02 [NCIt concept]
- Anti-PD-1/TGF-beta RII Bifunctional Fusion Protein JS201 [NCIt concept]
- Anti-PD-1/TGFbRII Fusion Protein LBL-015 [NCIt concept]
- Anti-PD1/IL-15 Fusion Protein SAR445877 [NCIt concept]
- Balstilimab [NCIt concept]
- Budigalimab [NCIt concept]
- Cadonilimab [NCIt concept]
- Caldonirimab [NCIt concept]
- Camrelizumab [NCIt concept]
- Cemiplimab [NCIt concept]
- Cetrelimab [NCIt concept]
- Copper Cu 64-DOTA-pembrolizumab [NCIt concept]
- Danvilostomig [NCIt concept]
- Dostarlimab [NCIt concept]
- Enlonstobart [NCIt concept]
- Ezabenlimab [NCIt concept]
- Favezelimab/Pembrolizumab Formulation [NCIt concept]
- Finotonlimab [NCIt concept]
- Geptanolimab [NCIt concept]
- Ivonescimab [NCIt concept]
- Izuralimab [NCIt concept]
- Latikafusp [NCIt concept]
- Lipustobart [NCIt concept]
- Lorigerlimab [NCIt concept]
- Nivolumab [NCIt concept]
- Nivolumab/Relatlimab-rmbw [NCIt concept]
- Nofazinlimab [NCIt concept]
- PD-1 Directed Probody CX-188 [NCIt concept]
- PD-1 Targeted IL-15 Mutein Fusion Protein PF-07209960 [NCIt concept]
- PD-1-positive B-cell Peptide Antigen/MVF IMU-201/Montanide Vaccine [NCIt concept]
- Pembrolizumab [NCIt concept]
- Pembrolizumab/Quavonlimab MK-1308A [NCIt concept]
- Penpulimab [NCIt concept]
- Pidilizumab [NCIt concept]
- Pimivalimab [NCIt concept]
- Pradusinstobart [NCIt concept]
- Prolgolimab [NCIt concept]
- Pucotenlimab [NCIt concept]
- Recombinant Human Hyaluronidase and Pembrolizumab [NCIt concept]
- Reozalimab [NCIt concept]
- Retifanlimab [NCIt concept]
- Rilvegostomig [NCIt concept]
- Rulonilimab [NCIt concept]
- Sasanlimab [NCIt concept]
- Serplulimab [NCIt concept]
- Sintilimab [NCIt concept]
- Spartalizumab [NCIt concept]
- Tebotelimab [NCIt concept]
- Tislelizumab [NCIt concept]
- Tobemstomig [NCIt concept]
- Toripalimab [NCIt concept]
- Vibostolimab/Pembrolizumab MK-7684A [NCIt concept]
- Volrustomig [NCIt concept]
- Zeluvalimab [NCIt concept]
- Zimberelimab [NCIt concept]

Keyword's position in hierarchy(ies) :

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