" /> Balstilimab - CISMeF





Preferred Label : Balstilimab;

NCIt definition : A monoclonal antibody directed against the negative immunoregulatory human cell surface receptor programmed cell death 1 (PD-1, PCD-1; PDCD1) protein, with potential immune checkpoint inhibitory and antineoplastic activities. Upon administration, balstilimab binds to PD-1, and thereby blocks its binding to the PD-1 ligand programmed cell death-1 ligand 1 (PD-L1), and prevents the activation of its downstream signaling pathways. This may restore immune function through the activation of cytotoxic T-cells. PD-1, a transmembrane protein in the immunoglobulin superfamily expressed on activated T-cells, negatively regulates T-cell activation and effector function when activated by its ligand; it plays an important role in tumor evasion from host immunity.;

UNII : 1Q2QT5M7EO;

CAS number : 2230167-06-1; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 2230167-06-1 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : AGEN 2034; AGEN-2034;

NCI Metathesaurus CUI : CL523768;

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12/05/2024


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