programmed cell death 1 receptor

Preferred Label : programmed cell death 1 receptor;

MeSH definition : An inhibitory T-lymphocyte receptor that has specificity for CD274 ANTIGEN and PROGRAMMED CELL DEATH 1 LIGAND 2 PROTEIN. Signaling by the receptor limits T cell proliferation and INTERFERON GAMMA synthesis. The receptor also may play an essential role in the regulatory pathway that induces PERIPHERAL TOLERANCE.;

MeSH synonym : programmed cell death 1 protein; PD-1 receptor; PD 1 receptor; receptor, PD-1; PD1 receptor; receptor, PD1; antigens, CD279; CD279 antigens; CD279 antigen; antigen, CD279; PD-1 Protein; PD 1 Protein; Programmed Cell Death Protein 1;

Is substance : O;

Details

Origin ID

D061026;

UMLS CUI

C2986635;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
Indexing information
- pembrolizumab [MeSH Supplementary Concept]
Record concept(s)
- programmed cell death 1 receptor [MeSH concept]
Related MeSH Supplementary Concept(s)
- PDCD1 protein, human [MeSH Supplementary Concept]
- Pdcd1 protein, mouse [MeSH Supplementary Concept]
See also
- Immunoglobulin Domains [MeSH Descriptor]
See also (suggested by CISMeF)
- Nivolumab [MeSH Descriptor]
- pembrolizumab [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Nivolumab [NCIt concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- Programmed Cell Death Protein 1 [NCIt concept]

Keyword's position in hierarchy(ies) :

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