Nucleotide-Binding Oligomerization Domain-Containing Protein 2

Preferred Label : Nucleotide-Binding Oligomerization Domain-Containing Protein 2;

NCIt synonyms : Caspase Recruitment Domain-Containing Protein 15; Inflammatory Bowel Disease Protein 1; NOD2;

NCIt definition : Nucleotide-binding oligomerization domain-containing protein 2 (1040 aa, 115 kDa) is encoded by the human NOD2 gene. This protein is involved in the activation of caspases and the immune response to bacterial challenge.;

Details

Origin ID

C74449;

UMLS CUI

C0967090;

OMIM relation
- Nucleotide-binding oligomerization domain protein 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- NOD2 protein, human [MeSH Supplementary Concept]
- NOD2 protein, human [MeSH concept]
gene_encodes_gene_product
- Apoptosis Regulation Gene [NCIt concept]
- NOD2 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_biochemical_function
- Apoptosis Promoter [NCIt concept]
- Regulatory Protein [NCIt concept]
gene_product_plays_role_in_biological_process
- Apoptosis [NCIt concept]
- Caspase-Dependent Apoptosis [NCIt concept]
- Positive Regulation of Apoptosis [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
- Microparticle MDP/Bacterial DNA-containing MIS416 [NCIt concept]

Keyword's position in hierarchy(ies) :

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