ACVR1C wt Allele

Preferred Label : ACVR1C wt Allele;

NCIt synonyms : ALK7; ACVRLK7; Activin A Receptor, Type IC wt Allele;

NCIt definition : Human ACVR1C wild-type allele is located in the vicinity of 2q24.1 and is approximately 102 kb in length. This allele, which encodes activin receptor type-1C protein, is involved in the mediation of protein phosphorylation and the modulation of cytokine signaling.;

NCIt note : Expression of the ACVR1C gene is downregulated in ovarian cancer. (J. Clin. Endocrinol. Metab. 2004; 89: 5523-5534.);

GenBank Accession Number : BC022530;

Details

Origin ID

C96020;

UMLS CUI

C3272499;

OMIM relation
- Activin a receptor, type ic [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_is_element_in_pathway
- TGF-beta Signaling Pathway KEGG [NCIt concept]
gene_plays_role_in_process
- Apoptosis [NCIt concept]
- Cell Differentiation Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Receptor Signaling [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients