BCL2L2 wt Allele

Preferred Label : BCL2L2 wt Allele;

NCIt synonyms : KIAA0271; BCL-W; BCL2-Like 2 Gene; BCLW; BCL2 Like 2 wt Allele;

NCIt definition : Human BCL2L2 wild-type allele is located within 14q11.2-q12 and is approximately 5kb in length. This allele, which encodes apoptosis regulator Bcl-W protein, is involved in apoptotic regulation.;

NCIt note : This gene encodes a member of the BCL-2 protein family. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons.;

GenBank Accession Number : NM_004050;

Details

Origin ID

C49351;

UMLS CUI

C1705393;

OMIM relation
- Bcl2-like 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 14: 22845866-22850798 [NCIt concept]
gene_in_chromosomal_location
- 14q11.2-q12 [NCIt concept]
gene_is_element_in_pathway
- Apoptosis Pathway [NCIt concept]
gene_plays_role_in_process
- Apoptosis [NCIt concept]
- Negative Regulation of Apoptosis [NCIt concept]

Keyword's position in hierarchy(ies) :

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