Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Rac Exchanger 1 Protein

Preferred Label : Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Rac Exchanger 1 Protein;

NCIt synonyms : P-Rex1; PtdIns(3,4,5)-Dependent Rac Exchanger 1; PREX1;

NCIt definition : Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (1659 aa, 186 kDa) is encoded by the human PREX1 gene. This protein is involved in the propagation of intracellular signaling through guanine nucleotide exchange activity.;

Details

Origin ID

C95296;

UMLS CUI

C2987043;

OMIM relation
- Phosphatidylinositol 3,4,5-trisphosphate-dependent rac exchanger 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_encodes_gene_product
- PREX1 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- DH Domain [NCIt concept]
- PDZ Domain [NCIt concept]
- PH Domain [NCIt concept]
gene_product_is_element_in_pathway
- Chemokine Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Apoptosis [NCIt concept]
- Cytoskeletal Modeling [NCIt concept]
- Post-Translational Modification [NCIt concept]
- Signal Transduction [NCIt concept]

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