NCIt synonyms : Protein Kinase Eg3; Tyrosine-Protein Kinase MELK; hMELK; Protein Kinase PK38; pEg3 Kinase; hPK38;
NCIt definition : Maternal embryonic leucine zipper kinase (651 aa, 75 kDa) is encoded by the human
MELK gene. This protein plays a role in the mediation of protein phosphorylation that
regulates cell cycle, cell death and cell proliferation.;
NCIt note : According to UniProt, GO, and the literature, maternal embryonic leucine zipper kinase
may possess both non-receptor protein-tyrosine kinase activity (EC 2.7.10.2) and serine/threonine
kinase activity (EC 2.7.11.1).;