" /> Maternal Embryonic Leucine Zipper Kinase - CISMeF





Preferred Label : Maternal Embryonic Leucine Zipper Kinase;

NCIt synonyms : Protein Kinase Eg3; Tyrosine-Protein Kinase MELK; hMELK; Protein Kinase PK38; pEg3 Kinase; hPK38;

NCIt definition : Maternal embryonic leucine zipper kinase (651 aa, 75 kDa) is encoded by the human MELK gene. This protein plays a role in the mediation of protein phosphorylation that regulates cell cycle, cell death and cell proliferation.;

NCIt note : According to UniProt, GO, and the literature, maternal embryonic leucine zipper kinase may possess both non-receptor protein-tyrosine kinase activity (EC 2.7.10.2) and serine/threonine kinase activity (EC 2.7.11.1).;

NCI Metathesaurus CUI : CL523824;

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08/05/2025


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