Apoptosis-Associated Speck-Like Protein Containing A CARD

Preferred Label : Apoptosis-Associated Speck-Like Protein Containing A CARD;

NCIt synonyms : PYD and CARD Domain-Containing Protein; Caspase Recruitment Domain-Containing Protein 5; hASC; Target of Methylation-Induced Silencing 1;

NCIt definition : Apoptosis-associated speck-like protein containing a CARD (195 aa, 22 kDa) is encoded by the human PYCARD gene. This protein plays a role in promotion of caspase activation and the initiation of apoptosis.;

Details

Origin ID

C93109;

UMLS CUI

C1449321;

OMIM relation
- Pyd and card domain-containing protein [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- PYCARD protein, human [MeSH concept]
- PYCARD protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Apoptosis Regulation Gene [NCIt concept]
- PYCARD Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_biochemical_function
- Apoptosis Promoter [NCIt concept]
- Regulatory Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_element_in_pathway
- Cytosolic DNA-Sensing Pathway [NCIt concept]
- NOD-Like Receptor Signaling Pathway [NCIt concept]
- p53 Effector Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Apoptosis [NCIt concept]
- Caspase Activation [NCIt concept]
- Positive Regulation of Apoptosis [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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