Transcription Factor Dp-1

Preferred Label : Transcription Factor Dp-1;

NCIt synonyms : DRTF1; DRTF1-Polypeptide 1; E2F Dimerization Partner 1; TFDP1;

NCIt definition : Transcription factor Dp-1 (410 aa, 45 kDa) is encoded by the human TFDP1 gene. This protein plays a role in transcriptional regulation, apoptosis, and cell cycle progression.;

NCIt note : Transcription factor Dp-1 binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3'. (UniProt);

Details

Origin ID

C95883;

UMLS CUI

C1453726;

Automatic exact mappings (from CISMeF team)
- Transcription factor dp1 [OMIM gene]
- transcription factor DP1 [MeSH concept]
- transcription factor Dp-1 [HGNC gene]
- transcription factor dp1 [MeSH Descriptor]
OMIM relation
- Transcription factor dp1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- TFDP1 protein, human [MeSH Supplementary Concept]
- TFDP1 protein, human [MeSH concept]
- transcription factor DP1 [MeSH concept]
- transcription factor dp1 [MeSH Descriptor]
gene_encodes_gene_product
- Regulatory Gene [NCIt concept]
- TFDP1 Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
gene_product_is_element_in_pathway
- Cell Cycle Pathway [NCIt concept]
- Cyclin E Degradation Pathway [NCIt concept]
- Cyclin Regulation of Cell Cycle Pathway [NCIt concept]
- E2F Transcription Factor Pathway [NCIt concept]
- E2F1 Degradation Pathway [NCIt concept]
- G1 to S Transition Pathway [NCIt concept]
- G1/S Checkpoint Pathway [NCIt concept]
- IL2RB Pathway [NCIt concept]
- Regulation of Nuclear SMAD2/3 Signaling Pathway [NCIt concept]
- Regulation of Retinoblastoma Protein Pathway [NCIt concept]
- TGF-beta Signaling Pathway KEGG [NCIt concept]
- p27 Regulation Pathway [NCIt concept]
- p53 Effector Pathway [NCIt concept]
gene_product_is_physical_part_of
- DREAM Complex [NCIt concept]
gene_product_plays_role_in_biological_process
- Apoptosis [NCIt concept]
- Cell Cycle Regulation Process [NCIt concept]
- DNA Binding [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients