" /> Fenretinide - CISMeF





Preferred Label : Fenretinide;

NCIt synonyms : 4-(all-trans-retino-yl)aminophenol; 4-HPR; 4-Hydroxyphenylretinamide; all-trans-N-4'-hydroxyretinanilide; HPR-4; N-(4-hydroxyphenyl)retinamide; Fenretinimide; all-trans-N-(4-Hydroxyphenyl)retinamide;

NCIt related terms : all-trans-4'-hydroxyretinanilide;

NCIt definition : An orally-active synthetic phenylretinamide analogue of retinol (vitamin A) with potential antineoplastic and chemopreventive activities. Fenretinide binds to and activates retinoic acid receptors (RARs), thereby inducing cell differentiation and apoptosis in some tumor cell types. This agent also inhibits tumor growth by modulating angiogenesis-associated growth factors and their receptors and exhibits retinoid receptor-independent apoptotic properties. (NCI04);

Alternative definition : NCI-GLOSS: A substance being studied in the treatment and prevention of some types of cancer. Fenretinide may cause ceramide (a wax-like substance) to build up in tumor cells and kill them. It is a type of retinoid, which are substances related to vitamin A.;

UNII : 187EJ7QEXL;

InChIKey : AKJHMTWEGVYYSE-FXILSDISSA-N;

CAS number : 65646-68-6; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 65646-68-6 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : McN-R-1967;

Chemical formula : C26H33NO2;

NSC code : 374551;

ChEBI ID : CHEBI:42588;

Codes from synonyms : CDR0000045233; NSC0374551; 00056;

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12/05/2024


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