IFNA2 wt Allele

Preferred Label : IFNA2 wt Allele;

NCIt synonyms : Interferon, Alpha 2 wt Allele; IFNA; IFNA2B; Interferon, Alpha-2 Gene; INFA2; RP11-354P17.2; IFN-AlphaA;

NCIt definition : Human IFNA2 wild-type allele is located in the vicinity of 9p22 and is approximately 1 kb in length. This allele, which encodes interferon alpha-2 protein, plays a role in the regulation of the immune cell response to cytokines and viruses.;

NCIt note : The interferon genes are found in a cluster with telomeric 3-prime ends and exhibit the order: pter-IFNB- (IFNW1, IFNA21)- IFNWP15- IFNA4- IFNW9- IFNA7- IFNA10- FNWP18- IFNAP16- IFNA17- IFNA14- (IFNA22, IFNA5, IFNAP20, IFNA6, IFNA13, IFNA2)- (IFNA8, IFNW2, IFNWP19, IFNA1)- MTAP-cen.;

GenBank Accession Number : NM_000605;

Details

Origin ID

C52797;

UMLS CUI

C1708406;

Automatic exact mappings (from CISMeF team)
- Interferon alpha [LOINC component]
- Interferon alpha-2 [MeSH Descriptor]
- Interferon, alpha-1 [OMIM gene]
- interferon-alpha [MeSH Descriptor]
OMIM relation
- Interferon, alpha-2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 9: 21375396-21374254 [NCIt concept]
gene_in_chromosomal_location
- 9p22 [NCIt concept]
gene_is_element_in_pathway
- Autoimmune Thyroid Disease Pathway [NCIt concept]
- Autophagy Regulation Pathway [NCIt concept]
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- Cytosolic DNA-Sensing Pathway [NCIt concept]
- Jak-STAT Signaling Pathway [NCIt concept]
- Natural Killer Cell-Mediated Cytotoxicity Pathway [NCIt concept]
- RIG-I-Like Receptor Signaling Pathway [NCIt concept]
- Toll-Like Receptor Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Apoptosis [NCIt concept]
- Cell Proliferation Regulatory Process [NCIt concept]
- Cytokine Receptor Activation [NCIt concept]
- Cytokine Receptor Binding [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Inflammatory Response [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Interferon Signaling Process [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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