NACHT, LRR and PYD Domains-Containing Protein 3

Preferred Label : NACHT, LRR and PYD Domains-Containing Protein 3;

NCIt synonyms : Cold Autoinflammatory Syndrome 1 Protein; PYRIN-Containing APAF1-Like Protein 1; Angiotensin/Vasopressin Receptor AII/AVP-Like; Cryopyrin; NACHT LRR and PYD Domains-Containing Protein 3; NLRP3;

NCIt definition : NACHT, LRR and PYD domains-containing protein 3 (1034 aa, 118 kDa) is encoded by the human NLRP3 gene. This protein plays a role in the modulation of both inflammation and apoptosis.;

Details

Origin ID

C77204;

UMLS CUI

C1384660;

OMIM relation
- Nlr family, pyrin domain-containing 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- NLRP3 protein, human [MeSH concept]
- NLRP3 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- NCIt COVID-19 Clinical Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
gene_encodes_gene_product
- Apoptosis Regulation Gene [NCIt concept]
- NLRP3 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_biochemical_function
- Apoptosis Promoter [NCIt concept]
- Regulatory Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Leucine-Rich Repeat [NCIt concept]
gene_product_plays_role_in_biological_process
- Apoptosis [NCIt concept]
- Inflammatory Response [NCIt concept]
- Positive Regulation of Apoptosis [NCIt concept]
is_target
- Dapansutrile [NCIt concept]
- NLRP3 Agonist BMS-986299 [NCIt concept]
- NLRP3 Inhibitor DFV890 [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients