Ras Association Domain-Containing Protein 7

Preferred Label : Ras Association Domain-Containing Protein 7;

NCIt synonyms : RASSF7; HRAS1-Related Cluster Protein 1;

NCIt definition : Ras association domain-containing protein 7 (373 aa, 40 kDa) is encoded by the human RASSF7 gene. This protein plays a role in the inhibiting the activation of c-Jun N-terminal kinases (JNK) by dual specificity mitogen-activated protein kinase kinase 7 (MAP2K7), which prevents JNK-dependent apoptosis.;

NCI Metathesaurus CUI : CL937979;

Details

Origin ID

C158519;

UMLS CUI

C4761415;

Automatic exact mappings (from CISMeF team)
- Ras association domain family, member 7 [OMIM gene]
OMIM relation
- Ras association domain family, member 7 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
gene_encodes_gene_product
- Apoptosis Regulation Gene [NCIt concept]
- RASSF7 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoskeleton [NCIt concept]
gene_product_has_biochemical_function
- Apoptosis Inhibitor [NCIt concept]
- Regulatory Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Coiled-Coil Domain [NCIt concept]
- Proline-Rich Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Apoptosis [NCIt concept]
- Negative Regulation of Apoptosis [NCIt concept]
- Signal Transduction Inhibition [NCIt concept]

Keyword's position in hierarchy(ies) :

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