" /> Caspase-9 - CISMeF





Preferred Label : Caspase-9;

NCIt synonyms : CASP-9; CASP9 Protein; APAF-3; ICE-LAP6; Apoptotic Protease MCH-6; CASP9; ICE-Like Apoptotic Protease 6; Procaspase 9; Apoptotic Protease Activating Factor 3; Caspase 9, Apoptosis-Related Cysteine Protease; MCH6; APAF3; EC 3.4.22.62; Pro-Caspase-9; Pro-Caspase 9; Procaspase-9;

NCIt definition : Caspase-9 (416 aa, 46 kDa) is encoded by the human CASP9 gene. This protein is involved in proteolysis and caspase-dependent apoptosis.;

NCIt note : Caspase-9 can initiate a biochemical cascade involving the downstream executioners caspase-3, -6, and -7. (UniProt); Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme.;

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29/04/2024


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