NCIt definition : Human MAP2K6 wild-type allele is located in the vicinity of 17q24.3 and is approximately
129 kb in length. This allele, which encodes mitogen-activated protein kinase kinase
6 protein, is involved in cellular proliferation and is essential for the regulation
of the p38 mitogen-activated protein kinase signal cascade.;
NCIt note : The MAP2K6 gene is an essential component of p38 MAP kinase mediated signal transduction
pathway, and thus; plays a role in many cellular processes such as stress induced
cell cycle arrest, transcription activation and apoptosis.;