Eukaryotic Translation Initiation Factor 5A-1

Preferred Label : Eukaryotic Translation Initiation Factor 5A-1;

NCIt synonyms : eIF-5A-1; eIF-5A; eIF-4D; eIF-5A1; Rev-Binding Factor; Eukaryotic Initiation Factor 5A Isoform 1; EIF5A;

NCIt definition : Eukaryotic translation initiation factor 5A-1 (154 aa, 17 kDa) is encoded by the human EIF5A gene. This protein plays a role in both apoptosis and translation.;

NCIt note : Eukaryotic translation initiation factor 5A-1 is the only known eukaryotic protein to have an hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group. (UniProt);

Details

Origin ID

C91355;

UMLS CUI

C0283786;

OMIM relation
- Eukaryotic translation initiation factor 5a [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- EIF5A protein, human [MeSH concept]
- EIF5A protein, human [MeSH Supplementary Concept]
- eukaryotic translation initiation factor 5A [MeSH concept]
- eukaryotic translation initiation factor 5A [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- EIF5A Gene [NCIt concept]
- Translation Process Gene [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_plays_role_in_biological_process
- Apoptosis [NCIt concept]
- Translation Process [NCIt concept]
- Translational Regulation [NCIt concept]
is_target
- SNS01-T Nanoparticles [NCIt concept]

Keyword's position in hierarchy(ies) :

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