BBC3 wt Allele

Preferred Label : BBC3 wt Allele;

NCIt synonyms : PUMA; BCL2 Binding Component 3 wt Allele; JFY1; FLJ42994;

NCIt definition : Human BBC3 wild-type allele is located within 19q13.3-q13.4 and is approximately 12 kb in length. This allele, which encodes Bcl-2-binding component 3 protein, is involved in the modulation of apoptosis.;

NCIt note : The BBC3 gene is an essential modulator of p53-dependent and p53-independent apoptosis. (EntrezGene);

GenBank Accession Number : AF332558;

Details

Origin ID

C91773;

UMLS CUI

C2984550;

Currated CISMeF NLP mapping
- puma [MeSH Descriptor]
- puma [MeSH concept]
OMIM relation
- Bcl2-binding component 3 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 19q13.3-q13.4 [NCIt concept]
gene_is_element_in_pathway
- Huntington's Disease Pathway [NCIt concept]
- p53 Effector Pathway [NCIt concept]
- p53 Signaling Pathway KEGG [NCIt concept]
gene_plays_role_in_process
- Apoptosis [NCIt concept]
- Caspase Activation [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients