RIPK2 wt Allele

Preferred Label : RIPK2 wt Allele;

NCIt synonyms : CARD3; RICK; Receptor-Interacting Serine-Threonine Kinase 2 wt Allele; CARDIAK; RIP2;

NCIt definition : Human RIPK2 wild-type allele is located within 8q21 and is approximately 33 kb in length. This allele, which encodes receptor-interacting serine/threonine-protein kinase 2 protein, plays a role in promotion of apoptosis, activation of the transcription factor NF-kappa-B, and signaling involved in both the innate and adaptive immune response pathways.;

GenBank Accession Number : NM_003821;

Details

Origin ID

C51311;

UMLS CUI

C1706435;

OMIM relation
- Receptor-interacting serine/threonine kinase 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 8q21 [NCIt concept]
gene_is_element_in_pathway
- Canonical NF-kappaB Signaling Pathway [NCIt concept]
- Fas Signaling Pathway BioCarta [NCIt concept]
- IL12-Mediated Signaling Pathway [NCIt concept]
- NOD-Like Receptor Signaling Pathway [NCIt concept]
- Nerve Growth Factor Receptor Signaling Pathway [NCIt concept]
- Neurotrophin Signaling Pathway [NCIt concept]
- Shigellosis Pathway [NCIt concept]
gene_plays_role_in_process
- Apoptosis [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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