Protein-Tyrosine Kinase 2-Beta

Preferred Label : Protein-Tyrosine Kinase 2-Beta;

NCIt synonyms : Related Adhesion Focal Tyrosine Kinase; Proline-rich Tyrosine Kinase 2; RAFT Kinase; CAK Beta; PTK2B; Cell Adhesion Kinase Beta; PYK2 Kinase; PTK2B Protein Tyrosine Kinase 2 Beta; Calcium-Dependent Tyrosine Kinase; Calcium-Regulated Non-Receptor Proline-Rich Tyrosine Kinase; EC 2.7.10.2; CAKB; RAFTK; Focal Adhesion Kinase 2; CAK-Beta; FADK 2; CADTK; PTK2B Protein Tyrosine Kinase-2 Beta;

NCIt definition : Protein-tyrosine kinase 2-beta (1009 aa, 116 kDa) is encoded by the human PTK2B gene. This protein plays a role in tyrosine phosphorylation, signal transduction and the regulation of many cellular processes including apoptosis, cell migration, cell proliferation and cell adhesion.;

Details

Origin ID

C17978;

UMLS CUI

C1430595;

OMIM relation
- Protein-tyrosine kinase 2, beta [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- PTK2B protein, human [MeSH Supplementary Concept]
- PTK2B protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Kinase Family Gene [NCIt concept]
- PTK2B Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Proline-Rich Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
- Tyrosine Kinase Domain [NCIt concept]
gene_product_is_element_in_pathway
- Alpha-Synuclein Signaling Pathway [NCIt concept]
- Angiotensin II Signaling Pathway [NCIt concept]
- Bioactive Peptide Signaling Pathway [NCIt concept]
- CCR5 Signaling Pathway [NCIt concept]
- CXCR4 Signaling Pathway [NCIt concept]
- CXCR4-Mediated Signaling Pathway [NCIt concept]
- Calcium-Mediated Signaling Pathway [NCIt concept]
- Chemokine Signaling Pathway [NCIt concept]
- Coregulation Pathway for Androgen Receptor Activity [NCIt concept]
- Endothelin Pathway [NCIt concept]
- FGF Signaling Pathway [NCIt concept]
- Gonadotropin-Releasing Hormone Signaling Pathway [NCIt concept]
- HBx Signaling Pathway [NCIt concept]
- Hepatocyte Growth Factor Receptor Signaling Pathway BioCarta [NCIt concept]
- IL2-Mediated Signaling Pathway [NCIt concept]
- IL7 Signaling Pathway [NCIt concept]
- Integrin Angiogenesis Pathway [NCIt concept]
- Ion Channel and Phorbal Esters Signaling Pathway [NCIt concept]
- Leukocyte Transendothelial Migration Pathway [NCIt concept]
- Lysophosphatidic Acid Receptor Signaling Pathway [NCIt concept]
- Natural Killer Cell-Mediated Cytotoxicity Pathway [NCIt concept]
- Osteopontin-Mediated Signaling Pathway [NCIt concept]
- Pyk2 and Map Kinase Pathway [NCIt concept]
- Ras-Independent Cell-Mediated Cytotoxicity Pathway [NCIt concept]
- Regulation of Apoptosis Pathway [NCIt concept]
- Thrombin/Protease-Activated Receptor Signaling Pathway [NCIt concept]
- VEGFR1 and VEGFR2 Signaling [NCIt concept]
gene_product_plays_role_in_biological_process
- Apoptosis [NCIt concept]
- Cell Differentiation Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Proliferation [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Signal Transduction [NCIt concept]
- Stress Response Signaling [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]

Keyword's position in hierarchy(ies) :

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