CRADD wt Allele

Preferred Label : CRADD wt Allele;

NCIt synonyms : MRT34; RAIDD; RIP-Associated ICH1/CED3-Homologous Protein With Death Domain Gene; CASP2 and RIPK1 Domain Containing Adaptor with Death Domain wt Allele;

NCIt definition : Human CRADD wild-type allele is located in the vicinity of 12q22 and is approximately 217 kb in length. This allele, which encodes death domain-containing protein CRADD, is involved in the promotion of apoptosis. Mutation of the gene is associated with autosomal recessive intellectual developmental disorder 34 with variant lissencephaly.;

NCI Metathesaurus CUI : CL1799294;

GenBank Accession Number : U84388;

Détails

Origin ID

C190816;

UMLS CUI

C5781210;

OMIM relation
- Casp2 and ripk1 domain-containing adaptor with death domain [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 12q22 [NCIt concept]
gene_is_element_in_pathway
- Caspase Cascade in Apoptosis [NCIt concept]
- Ceramide Signaling Pathway PID [NCIt concept]
- HIV-1 Nef: Negative Effector Pathway for Fas and TNF-Alpha [NCIt concept]
gene_plays_role_in_process
- Apoptosis [NCIt concept]
- Caspase Activation [NCIt concept]
- Positive Regulation of Apoptosis [NCIt concept]

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