" /> PTK2 wt Allele - CISMeF





Preferred Label : PTK2 wt Allele;

NCIt synonyms : PTK2 Protein Tyrosine Kinase 2 wt Allele; FAK1; FADK; FAK; pp125FAK;

NCIt definition : Human PTK2 wild-type allele is located within 8q24-qter and is approximately 343 kb in length. This allele, which encodes focal adhesion kinase 1 protein, plays a role in the transduction of adhesion-dependent signals and is involved in adhesion-dependent cell survival signaling. The PTK2 gene is overexpressed in a number of types of cancer such as breast, cervical, colorectal, ovarian, prostate, and thyroid cancers.;

NCIt note : Although the PTK2 gene is ubiquitously expressed, the highest levels of gene products are detected in the brain. Focal adhesion kinase 1 protein is localized in focal adhesions that form between cells.;

GenBank Accession Number : NM_153831;

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20/05/2024


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