DCC wt Allele - CISMeF

Preferred Label : DCC wt Allele;

NCIt synonyms : Colorectal Cancer-Related Chromosome Sequence 18; Deleted in Colorectal Carcinoma; Deleted in Colorectal Carcinoma wt Allele; DCC; CRC18; Immunoglobulin Superfamily, DCC Subclass, Member 1 Gene; IGDCC1; NTN1R1; CRCR1; MRMV1;

NCIt definition : Human DCC wild-type allele is located in the vicinity of 18q21.3 and is approximately 1190 kb in length. This allele, which encodes netrin receptor DCC protein, plays a role in both axonal guidance and neuronal growth cone formation. Mutation of this gene may be associated with both colorectal and esophageal carcinomas.;

GenBank Accession Number : X76132;

Details

Origin ID

C54427;

UMLS CUI

C1704789;

OMIM relation
- Dcc netrin 1 receptor [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_associated_with_disease
- Colorectal Carcinoma [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 18: 48121156-49311286 [NCIt concept]
gene_in_chromosomal_location
- 18q21.3 [NCIt concept]
gene_is_element_in_pathway
- Axon Guidance Pathway [NCIt concept]
- Colorectal Cancer Pathway [NCIt concept]
gene_plays_role_in_process
- Apoptosis [NCIt concept]
- Ligand Binding [NCIt concept]
- Neural Development [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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