Tumor Protein D53

Preferred Label : Tumor Protein D53;

NCIt synonyms : hD53; D52-Like 1; D53; TPD52L1; Tumor Protein-D52-Like-1 Protein; Tumor Protein D52-Like 1;

NCIt definition : Tumor protein D53 (204 aa, 22 kDa) is encoded by the human TPD52L1 gene. This protein plays a role in apoptosis.;

NCIt note : Tumor protein D53 exhibits 52% identity to D52, a coiled-coil domain, and PEST domains. D52, D53, and D54 share significant homology, including a coiled-coil domain indicative of protein-protein interactions. TPD52L1 forms homodimers, or heterodimers with other family members. Like D52, TPD52L1 may be involved in calcium-mediated signal transduction and cell proliferation.;

Details

Origin ID

C30117;

UMLS CUI

C1314855;

OMIM relation
- Tumor protein d52-like 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- TPD52L1 protein, human [MeSH Supplementary Concept]
- TPD52L1 protein, human [MeSH concept]
gene_encodes_gene_product
- Regulatory Gene [NCIt concept]
- TPD52L1 Gene [NCIt concept]
gene_product_plays_role_in_biological_process
- Apoptosis [NCIt concept]
- Protein-Protein Interaction [NCIt concept]

Keyword's position in hierarchy(ies) :

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