Interleukin-1 Beta

Preferred Label : Interleukin-1 Beta;

NCIt synonyms : IL1B; Catabolin; IL1-Beta; IL1B Protein; Interleukin 1, Beta Proprotein; IL-1-b; Interleukin 1-Beta; IL1F2; Interleukin 1, Beta; Preinterleukin 1 Beta; IL-1 Beta;

NCIt related terms : IL-1B; IL-1-beta; interleukin-1-beta;

NCIt definition : Interleukin-1 beta (269 aa, 31 kDa) is encoded by the human IL1B gene. This protein is involved in the macrophage-dependent inflammatory response.;

Codes from synonyms : CDR0000624949; CDR0000624952; CDR0000624953;

Details

Origin ID

C20522;

UMLS CUI

C1702300;

False automatic mappings
- Interleukin-1 beta (substance) [SNOMED CT concept]
OMIM relation
- Interleukin 1-beta [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- IL1B protein, human [MeSH concept]
- IL1B protein, human [MeSH Supplementary Concept]
- Interleukin 1 beta [LOINC component]
- Interleukin-1 beta (substance) [SNOMED CT concept]
- Interleukin-1beta [MeSH concept]
- Interleukin-1beta [MeSH Descriptor]
Validated automatic mappings to NTBT
- interleukin 1 [COVID-19 Thesaurus concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
endogenous_product_related_to
- Recombinant Interleukin-1-beta [NCIt concept]
gene_encodes_gene_product
- Cytokine Gene [NCIt concept]
- IL1B Gene [NCIt concept]
- Interleukin Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_chemical_classification
- Interleukin-1 [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_element_in_pathway
- Alzheimer's Disease Pathway KEGG [NCIt concept]
- Amoebiasis Pathway [NCIt concept]
- Apoptosis Pathway [NCIt concept]
- Cellular Anthrax Toxin Pathway [NCIt concept]
- Chagas Disease Pathway [NCIt concept]
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- Cytosolic DNA-Sensing Pathway [NCIt concept]
- Graft-Versus-Host Disease Pathway [NCIt concept]
- Hematopoietic Cell Lineage Pathway [NCIt concept]
- IL1-Mediated Signaling Pathway [NCIt concept]
- IL1R Signaling Pathway [NCIt concept]
- IL23-Mediated Signaling Pathway [NCIt concept]
- IL27-Mediated Signaling Pathway [NCIt concept]
- IL5 Signaling Pathway [NCIt concept]
- Interferon-Gamma Signaling Pathway [NCIt concept]
- Leishmaniasis Infection Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- Macrophage Stimulating 1 Receptor Signaling Pathway [NCIt concept]
- Malaria Pathway [NCIt concept]
- NFKB Activation Pathway [NCIt concept]
- NOD-Like Receptor Signaling Pathway [NCIt concept]
- Prion Disease Pathway [NCIt concept]
- Salmonella Pathway [NCIt concept]
- Toll-Like Receptor Signaling Pathway [NCIt concept]
- Type I Diabetes Mellitus Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Apoptosis [NCIt concept]
- Cell Differentiation Process [NCIt concept]
- Cell Proliferation [NCIt concept]
- Cell Proliferation Regulatory Process [NCIt concept]
- Cytokine Receptor Activation [NCIt concept]
- Cytokine Receptor Binding [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Inflammatory Response [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Interleukin Signaling Process [NCIt concept]
is_target
- Anti-interleukin-1 Beta Monoclonal Antibody AK114 [NCIt concept]
- Anti-interleukin-1 Beta Monoclonal Antibody FL-101 [NCIt concept]
- Canakinumab [NCIt concept]
- Gevokizumab [NCIt concept]

Keyword's position in hierarchy(ies) :

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