Gevokizumab - CISMeF

Preferred Label : Gevokizumab;

NCIt synonyms : Immunoglobulin G2, anti-(human interleukin 1-beta) (human-Mus musculus XOMA 052 heavy chain), disulfide with human-Mus musculus XOMA 052 kappa-chain, Dimer;

NCIt definition : An IgG2 humanized monoclonal antibody against the pro-inflammatory cytokine interleukin 1 beta (IL-1b) with anti-inflammatory activity. Gevokizumab binds to IL-1b, thereby preventing IL-1b-mediated inflammatory responses. This antibody has a long half life and allows for once a month dosing intervals.;

UNII : QX3JU54GYQ;

CAS number : 1129435-60-4;

Molecule name : XOMA 052;

Details

Origin ID

C97945;

UMLS CUI

C3179523;

Currated CISMeF NLP mapping
- gevokizumab [MeSH concept]
- gevokizumab [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- gevokizumab [MeSH concept]
- gevokizumab [MeSH Supplementary Concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_target
- Interleukin-1 Beta [NCIt concept]

Keyword's position in hierarchy(ies) :

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