Caveolin-2 - CISMeF

Preferred Label : Caveolin-2;

NCIt synonyms : CAV2; Caveolae Protein, 20-kD; Caveolin 2; Caveolin 2 Isoform A and B;

NCIt definition : Caveolin-2 (162 aa, 18 kDa) is encoded by the human CAV2 gene. This protein plays a role in caveolae formation and function.;

NCIt note : Caveolins interact with G proteins and link alpha integrin to FYN tyrosine kinase, SHC, GRB2 and the RAS-ERK pathway in promoting cell cycle progression.;

Détails

Origin ID

C21586;

UMLS CUI

C1564968;

Currated CISMeF NLP mapping
- caveolin 2 [MeSH Descriptor]
- caveolin 2 [MeSH concept]
OMIM relation
- Caveolin 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- CAV2 protein, human [MeSH concept]
- CAV2 protein, human [MeSH Supplementary Concept]
- caveolin 2 [MeSH concept]
- caveolin 2 [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CAV2 Gene [NCIt concept]
- Structural Protein Gene [NCIt concept]
gene_product_expressed_in_tissue
- Endothelial Cell [NCIt concept]
- Fibroblast [NCIt concept]
- Smooth Muscle Cell [NCIt concept]
gene_product_has_associated_anatomy
- Caveola [NCIt concept]
gene_product_has_biochemical_function
- Signaling Protein [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_element_in_pathway
- Bacterial Invasion of Epithelial Cell Pathway [NCIt concept]
- Endocytosis Pathway [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
- Syndecan-2-Mediated Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Apoptosis [NCIt concept]
- Cell Growth Regulation [NCIt concept]
- Receptor Mediated Endocytosis [NCIt concept]
- Signal Transduction [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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