Serine/Threonine-Protein Kinase B-Raf - CISMeF

" /> Serine/Threonine-Protein Kinase B-Raf - CISMeF

CISMeF

chu

Serine/Threonine-Protein Kinase B-RafNCIt concept

Preferred Label : Serine/Threonine-Protein Kinase B-Raf;

NCIt synonyms : BRAF1 Protein; RAFB1 Protein; B-RAF Serine/Threonine Protein Kinase; BRAF Protein; KRAB Protein; BRAF; Proto-Oncogene B-Raf; EC 2.7.11.1; v-Raf Murine Sarcoma Viral Oncogene Homolog B1; p94; 94 kDa B-raf Protein; B-RAF Protein Kinase;

NCIt definition : Serine/threonine-protein kinase B-raf (766 aa, 84 kDa) is encoded by the human BRAF gene. This protein plays a role in protein phosphorylation, mitogenesis and neuronal signal transduction.;

Details

Origin ID

C17476;

UMLS CUI

C1259929;

Automatic exact mappings (from CISMeF team)
- B-Raf proto-oncogene, serine/threonine kinase [ORDO Gene]
- B-raf protooncogene, serine/threonine kinase [OMIM gene]
- BRAF protein [LOINC component]
- Calpain 3 [OMIM gene]
- calpain 3 [ORDO Gene]
- proto-oncogene proteins b-raf [MeSH Descriptor]
OMIM relation
- B-raf protooncogene, serine/threonine kinase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- BRAF protein, human [MeSH Supplementary Concept]
- BRAF protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- BRAF Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_expressed_in_tissue
- Supratentorial Brain [NCIt concept]
- Testis [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
- Serine/Threonine Protein Kinase [NCIt concept]
gene_product_has_gene_product_variant
- Activating BRAF NP_004324.2:p.V600X [NCIt concept]
- BRAF NP_004324.2:p.A320V [NCIt concept]
- BRAF NP_004324.2:p.G466A [NCIt concept]
- BRAF NP_004324.2:p.G466E [NCIt concept]
- BRAF NP_004324.2:p.G466R [NCIt concept]
- BRAF NP_004324.2:p.G466V [NCIt concept]
- BRAF NP_004324.2:p.G469A [NCIt concept]
- BRAF NP_004324.2:p.G469E [NCIt concept]
- BRAF NP_004324.2:p.G469R [NCIt concept]
- BRAF NP_004324.2:p.G469S [NCIt concept]
- BRAF NP_004324.2:p.G469V [NCIt concept]
- BRAF NP_004324.2:p.G469X [NCIt concept]
- BRAF NP_004324.2:p.K601E [NCIt concept]
- BRAF NP_004324.2:p.L485X [NCIt concept]
- BRAF NP_004324.2:p.L597Q [NCIt concept]
- BRAF NP_004324.2:p.L597R [NCIt concept]
- BRAF NP_004324.2:p.L597S [NCIt concept]
- BRAF NP_004324.2:p.L597V [NCIt concept]
- BRAF NP_004324.2:p.L597X [NCIt concept]
- BRAF NP_004324.2:p.T599_V600insT [NCIt concept]
- BRAF NP_004324.2:p.V504_R506dup [NCIt concept]
- BRAF NP_004324.2:p.V600A [NCIt concept]
- BRAF NP_004324.2:p.V600D [NCIt concept]
- BRAF NP_004324.2:p.V600E [NCIt concept]
- BRAF NP_004324.2:p.V600G [NCIt concept]
- BRAF NP_004324.2:p.V600K [NCIt concept]
- BRAF NP_004324.2:p.V600L [NCIt concept]
- BRAF NP_004324.2:p.V600M [NCIt concept]
- BRAF NP_004324.2:p.V600R [NCIt concept]
- BRAF NP_004324.2:p.V600X [NCIt concept]
- BRAF Protein Variant [NCIt concept]
gene_product_has_structural_domain_or_motif
- DAG/PE-Binding Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- Acute Myeloid Leukemia Pathway [NCIt concept]
- Bladder Cancer Pathway [NCIt concept]
- Chemokine Signaling Pathway [NCIt concept]
- Chronic Myeloid Leukemia Pathway [NCIt concept]
- Colorectal Cancer Pathway [NCIt concept]
- ERBB Family Signaling Pathway [NCIt concept]
- Endometrial Cancer Pathway [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
- Glioblastoma Multiforme Pathway [NCIt concept]
- Insulin/Insulin Receptor Signaling Pathway [NCIt concept]
- Long-Term Depression Pathway [NCIt concept]
- Long-Term Potentiation Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- MAPKinase Signaling Pathway [NCIt concept]
- Melanoma Pathway [NCIt concept]
- NTRK1/MAPK Signaling Pathway [NCIt concept]
- Natural Killer Cell-Mediated Cytotoxicity Pathway [NCIt concept]
- Neurotrophin Signaling Pathway [NCIt concept]
- Non-Small Cell Lung Cancer Pathway [NCIt concept]
- Pancreatic Cancer Pathway [NCIt concept]
- Papillary Thyroid Carcinoma Pathway [NCIt concept]
- Progesterone-Mediated Oocyte Maturation Pathway [NCIt concept]
- Prostate Cancer Pathway [NCIt concept]
- Ras Signaling in the CD4+ TCR Pathway [NCIt concept]
- Renal Cell Carcinoma Pathway [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD8+ T Cells [NCIt concept]
- Vascular Smooth Muscle Contraction Pathway [NCIt concept]
- mTOR Signaling Pathway KEGG [NCIt concept]
gene_product_plays_role_in_biological_process
- Angiogenic Process [NCIt concept]
- Apoptosis [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
- Agerafenib [NCIt concept]
- B-Raf/VEGFR-2 Inhibitor RAF265 [NCIt concept]
- BRAF Inhibitor [NCIt concept]
- BRAF Inhibitor ARQ 736 [NCIt concept]
- BRAF Inhibitor BGB-3245 [NCIt concept]
- BRAF Inhibitor LUT014 [NCIt concept]
- BRAF Inhibitor PF-07799933 [NCIt concept]
- BRAF V600E Degrader CFT1946 [NCIt concept]
- BRAF V600E Inhibitor HLX208 [NCIt concept]
- BRAF(V600E) Kinase Inhibitor ABM-1310 [NCIt concept]
- BRAF(V600E) Kinase Inhibitor RO5212054 [NCIt concept]
- BRAF585-614 (V600E) Peptide [NCIt concept]
- BRAFV600/PI3K Inhibitor ASN003 [NCIt concept]
- Dabrafenib [NCIt concept]
- Dabrafenib Mesylate [NCIt concept]
- Encorafenib [NCIt concept]
- Exarafenib [NCIt concept]
- Lifirafenib [NCIt concept]
- Naporafenib [NCIt concept]
- Pan-RAF Inhibitor LY3009120 [NCIt concept]
- Plixorafenib [NCIt concept]
- RAF Inhibitor BDTX-4933 [NCIt concept]
- RAF Kinase Inhibitor XL281 [NCIt concept]
- Sorafenib [NCIt concept]
- Sorafenib Tosylate [NCIt concept]
- Tinlorafenib [NCIt concept]
- Tovorafenib [NCIt concept]
- Vemurafenib [NCIt concept]
- pan-RAF Inhibitor JZP815 [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients

Nous contacter.
28/04/2024

© Rouen University Hospital. Any partial or total use of this material must mention the source.

" /> Serine/Threonine-Protein Kinase B-Raf - CISMeF

CISMeF

chu

Serine/Threonine-Protein Kinase B-RafNCIt concept

Preferred Label : Serine/Threonine-Protein Kinase B-Raf;

NCIt synonyms : BRAF1 Protein; RAFB1 Protein; B-RAF Serine/Threonine Protein Kinase; BRAF Protein; KRAB Protein; BRAF; Proto-Oncogene B-Raf; EC 2.7.11.1; v-Raf Murine Sarcoma Viral Oncogene Homolog B1; p94; 94 kDa B-raf Protein; B-RAF Protein Kinase;

NCIt definition : Serine/threonine-protein kinase B-raf (766 aa, 84 kDa) is encoded by the human BRAF gene. This protein plays a role in protein phosphorylation, mitogenesis and neuronal signal transduction.;

Details

Origin ID

C17476;

UMLS CUI

C1259929;

Automatic exact mappings (from CISMeF team)
- B-Raf proto-oncogene, serine/threonine kinase [ORDO Gene]
- B-raf protooncogene, serine/threonine kinase [OMIM gene]
- BRAF protein [LOINC component]
- Calpain 3 [OMIM gene]
- calpain 3 [ORDO Gene]
- proto-oncogene proteins b-raf [MeSH Descriptor]
OMIM relation
- B-raf protooncogene, serine/threonine kinase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- BRAF protein, human [MeSH Supplementary Concept]
- BRAF protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- BRAF Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_expressed_in_tissue
- Supratentorial Brain [NCIt concept]
- Testis [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
- Serine/Threonine Protein Kinase [NCIt concept]
gene_product_has_gene_product_variant
- Activating BRAF NP_004324.2:p.V600X [NCIt concept]
- BRAF NP_004324.2:p.A320V [NCIt concept]
- BRAF NP_004324.2:p.G466A [NCIt concept]
- BRAF NP_004324.2:p.G466E [NCIt concept]
- BRAF NP_004324.2:p.G466R [NCIt concept]
- BRAF NP_004324.2:p.G466V [NCIt concept]
- BRAF NP_004324.2:p.G469A [NCIt concept]
- BRAF NP_004324.2:p.G469E [NCIt concept]
- BRAF NP_004324.2:p.G469R [NCIt concept]
- BRAF NP_004324.2:p.G469S [NCIt concept]
- BRAF NP_004324.2:p.G469V [NCIt concept]
- BRAF NP_004324.2:p.G469X [NCIt concept]
- BRAF NP_004324.2:p.K601E [NCIt concept]
- BRAF NP_004324.2:p.L485X [NCIt concept]
- BRAF NP_004324.2:p.L597Q [NCIt concept]
- BRAF NP_004324.2:p.L597R [NCIt concept]
- BRAF NP_004324.2:p.L597S [NCIt concept]
- BRAF NP_004324.2:p.L597V [NCIt concept]
- BRAF NP_004324.2:p.L597X [NCIt concept]
- BRAF NP_004324.2:p.T599_V600insT [NCIt concept]
- BRAF NP_004324.2:p.V504_R506dup [NCIt concept]
- BRAF NP_004324.2:p.V600A [NCIt concept]
- BRAF NP_004324.2:p.V600D [NCIt concept]
- BRAF NP_004324.2:p.V600E [NCIt concept]
- BRAF NP_004324.2:p.V600G [NCIt concept]
- BRAF NP_004324.2:p.V600K [NCIt concept]
- BRAF NP_004324.2:p.V600L [NCIt concept]
- BRAF NP_004324.2:p.V600M [NCIt concept]
- BRAF NP_004324.2:p.V600R [NCIt concept]
- BRAF NP_004324.2:p.V600X [NCIt concept]
- BRAF Protein Variant [NCIt concept]
gene_product_has_structural_domain_or_motif
- DAG/PE-Binding Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- Acute Myeloid Leukemia Pathway [NCIt concept]
- Bladder Cancer Pathway [NCIt concept]
- Chemokine Signaling Pathway [NCIt concept]
- Chronic Myeloid Leukemia Pathway [NCIt concept]
- Colorectal Cancer Pathway [NCIt concept]
- ERBB Family Signaling Pathway [NCIt concept]
- Endometrial Cancer Pathway [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
- Glioblastoma Multiforme Pathway [NCIt concept]
- Insulin/Insulin Receptor Signaling Pathway [NCIt concept]
- Long-Term Depression Pathway [NCIt concept]
- Long-Term Potentiation Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- MAPKinase Signaling Pathway [NCIt concept]
- Melanoma Pathway [NCIt concept]
- NTRK1/MAPK Signaling Pathway [NCIt concept]
- Natural Killer Cell-Mediated Cytotoxicity Pathway [NCIt concept]
- Neurotrophin Signaling Pathway [NCIt concept]
- Non-Small Cell Lung Cancer Pathway [NCIt concept]
- Pancreatic Cancer Pathway [NCIt concept]
- Papillary Thyroid Carcinoma Pathway [NCIt concept]
- Progesterone-Mediated Oocyte Maturation Pathway [NCIt concept]
- Prostate Cancer Pathway [NCIt concept]
- Ras Signaling in the CD4+ TCR Pathway [NCIt concept]
- Renal Cell Carcinoma Pathway [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD8+ T Cells [NCIt concept]
- Vascular Smooth Muscle Contraction Pathway [NCIt concept]
- mTOR Signaling Pathway KEGG [NCIt concept]
gene_product_plays_role_in_biological_process
- Angiogenic Process [NCIt concept]
- Apoptosis [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
- Agerafenib [NCIt concept]
- B-Raf/VEGFR-2 Inhibitor RAF265 [NCIt concept]
- BRAF Inhibitor [NCIt concept]
- BRAF Inhibitor ARQ 736 [NCIt concept]
- BRAF Inhibitor BGB-3245 [NCIt concept]
- BRAF Inhibitor LUT014 [NCIt concept]
- BRAF Inhibitor PF-07799933 [NCIt concept]
- BRAF V600E Degrader CFT1946 [NCIt concept]
- BRAF V600E Inhibitor HLX208 [NCIt concept]
- BRAF(V600E) Kinase Inhibitor ABM-1310 [NCIt concept]
- BRAF(V600E) Kinase Inhibitor RO5212054 [NCIt concept]
- BRAF585-614 (V600E) Peptide [NCIt concept]
- BRAFV600/PI3K Inhibitor ASN003 [NCIt concept]
- Dabrafenib [NCIt concept]
- Dabrafenib Mesylate [NCIt concept]
- Encorafenib [NCIt concept]
- Exarafenib [NCIt concept]
- Lifirafenib [NCIt concept]
- Naporafenib [NCIt concept]
- Pan-RAF Inhibitor LY3009120 [NCIt concept]
- Plixorafenib [NCIt concept]
- RAF Inhibitor BDTX-4933 [NCIt concept]
- RAF Kinase Inhibitor XL281 [NCIt concept]
- Sorafenib [NCIt concept]
- Sorafenib Tosylate [NCIt concept]
- Tinlorafenib [NCIt concept]
- Tovorafenib [NCIt concept]
- Vemurafenib [NCIt concept]
- pan-RAF Inhibitor JZP815 [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients

Nous contacter.
28/04/2024

© Rouen University Hospital. Any partial or total use of this material must mention the source.